Respiratory function in uncomplicated type 1 diabetes: Blunted during exercise even though normal at rest!
diffusion capacity
maximal exercise
micro-macrovascular complication
pulmonary function
spirometry
type 1 diabetes
ventilatory response
Journal
Diabetic medicine : a journal of the British Diabetic Association
ISSN: 1464-5491
Titre abrégé: Diabet Med
Pays: England
ID NLM: 8500858
Informations de publication
Date de publication:
05 2023
05 2023
Historique:
revised:
27
12
2022
received:
10
11
2022
accepted:
29
12
2022
medline:
13
4
2023
pubmed:
1
1
2023
entrez:
31
12
2022
Statut:
ppublish
Résumé
Type 1 diabetes is associated with a substantially increased risk of impaired lung function, which may impair aerobic fitness. We therefore aimed to examine the ventilatory response during maximal exercise and the pulmonary diffusion capacity function at rest in individuals with uncomplicated type 1 diabetes. In all, 17 adults with type 1 diabetes free from micro-macrovascular complications (glycated haemoglobin: 8.0 ± 1.3%), and 17 non-diabetic adults, carefully matched to the type 1 diabetes group according to gender, age, level of physical activity and body composition, participated in our study. Lung function was assessed by spirometry and measurements of the combined diffusing capacity for nitric oxide (DLNO) and carbon monoxide (DLCO) at rest. Subjects performed a maximal exercise test during which the respiratory parameters were measured. At rest, DLCO (30.4 ± 6.1 ml min Individuals with uncomplicated type 1 diabetes display normal alveolar-capillary diffusion capacity and at rest, while their forced vital capacity, tidal volumes and VO
Banques de données
ClinicalTrials.gov
['NCT02051504']
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e15036Informations de copyright
© 2022 The Authors. Diabetic Medicine published by John Wiley & Sons Ltd on behalf of Diabetes UK.
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