Fbxo2
Cochlea
CreER/LoxP
Fbx2
Fbxo2
Utricle
Vestibular
Journal
Hearing research
ISSN: 1878-5891
Titre abrégé: Hear Res
Pays: Netherlands
ID NLM: 7900445
Informations de publication
Date de publication:
02 2023
02 2023
Historique:
received:
21
08
2022
revised:
12
12
2022
accepted:
26
12
2022
pmc-release:
01
02
2024
pubmed:
2
1
2023
medline:
18
1
2023
entrez:
1
1
2023
Statut:
ppublish
Résumé
The mammalian inner ear contains six sensory patches that allow detection of auditory stimuli as well as movement and balance. Much research has focused on the organ of Corti, the sensory organ of the cochlea that detects sound. Unfortunately, these cells are difficult to access in vivo, especially in the mature animal, but the development of genetically modified mouse models, including Cre/Lox mice, has improved the ability to label, purify or manipulate these cells. Here, we describe a new tamoxifen-inducible CreER mouse line, the Fbxo2
Identifiants
pubmed: 36587458
pii: S0378-5955(22)00254-4
doi: 10.1016/j.heares.2022.108686
pmc: PMC9840692
mid: NIHMS1861819
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
108686Subventions
Organisme : NIDCD NIH HHS
ID : R01 DC013771
Pays : United States
Organisme : NIDCD NIH HHS
ID : R01 DC014832
Pays : United States
Informations de copyright
Copyright © 2022 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest Stefan Heller is a paid consultant for Pipeline Therapeutics and Lineage Therapeutics. No other authors declare significant competing interests.
Références
Development. 2006 Feb;133(4):663-73
pubmed: 16421190
Curr Top Dev Biol. 2018;130:217-244
pubmed: 29853178
J Assoc Res Otolaryngol. 2017 Apr;18(2):227-245
pubmed: 27873085
Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):1027-32
pubmed: 17209010
Semin Cell Dev Biol. 2017 May;65:96-105
pubmed: 27864084
Dev Biol. 2018 Nov 1;443(1):64-77
pubmed: 30179592
Neuron. 2015 Mar 04;85(5):942-58
pubmed: 25741722
J Physiol. 2006 Oct 1;576(Pt 1):11-21
pubmed: 16857713
Annu Rev Neurosci. 2011;34:501-34
pubmed: 21469959
J Neurosci. 2007 May 9;27(19):5163-71
pubmed: 17494702