Successful heparin-perfusion therapy for complete thrombosis of the intra- and extrahepatic portal and mesenteric vein. A case report and literature review.
Complications
Interventional radiology
Pathophysiology
Portal vein occlusion
Portal vein thrombosis
Journal
Radiology case reports
ISSN: 1930-0433
Titre abrégé: Radiol Case Rep
Pays: Netherlands
ID NLM: 101467888
Informations de publication
Date de publication:
Mar 2023
Mar 2023
Historique:
received:
30
10
2022
revised:
14
11
2022
accepted:
16
11
2022
entrez:
2
1
2023
pubmed:
3
1
2023
medline:
3
1
2023
Statut:
epublish
Résumé
The initial treatment of acute and subacute portal vein thrombosis, which is the most common cause of portal vein occlusion, consists of intravenous anticoagulation with heparin, but there is still a huge uncertainty among physicians regarding the role of more invasive therapies. We report a 61-year-old male patient, who presented in our emergency room with a subacute complete thrombosis of the intra- and extrahepatic portal vein, mesenteric vein, with associated venous congestion of 20-30 cm length of the small intestine with a quick and complete remission of the portal vein thrombosis under sole i.v. heparin-perfusor therapy without any complications. Molecular genetic analysis found combined genetic mutations of the gene factor 2 (c.20210G>A, heterozygotic), SERPINE1 (-675 5G>4G, heterozygotic), and the MTHFR gene. Along with this interesting case, we also present the recent status of portal vein thrombosis and portal vein occlusion in the literature.
Identifiants
pubmed: 36589499
doi: 10.1016/j.radcr.2022.11.052
pii: S1930-0433(22)01023-8
pmc: PMC9800246
doi:
Types de publication
Case Reports
Langues
eng
Pagination
850-855Informations de copyright
© 2022 The Authors. Published by Elsevier Inc. on behalf of University of Washington.
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