Microenvironment changes in arteriovenous malformations after stereotactic radiation.

arteriovenous malformation changes after radiation in AVMs microenvironment changes in AVM radiation for AVM stereotactic radiosurgery for AVM

Journal

Frontiers in human neuroscience
ISSN: 1662-5161
Titre abrégé: Front Hum Neurosci
Pays: Switzerland
ID NLM: 101477954

Informations de publication

Date de publication:
2022
Historique:
received: 30 06 2022
accepted: 23 11 2022
entrez: 2 1 2023
pubmed: 3 1 2023
medline: 3 1 2023
Statut: epublish

Résumé

Cerebral arteriovenous malformations are dysplastic vascular tangles with aberrant vascular dynamics and can result significant morbidity and mortality. A myriad of challenges are encountered when treating these lesions and are largely based on nidal size, location, and prior hemorrhage. Currently, stereotactic radiosurgery is an accepted form of treatment for small to medium sized lesions and is especially useful in the treatment of lesions in non-surgically assessable eloquent areas of the brain. Despite overall high rates of nidal obliteration, there is relatively limited understand on the mechanisms that drive the inflammatory and obliterative pathways observed after treatment with stereotactic radiosurgery. This review provides an overview of arteriovenous malformations with respect to stereotactic radiosurgery and the current understanding of the mechanisms that lead to nidal obliteration.

Identifiants

pubmed: 36590065
doi: 10.3389/fnhum.2022.982190
pmc: PMC9797682
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

982190

Informations de copyright

Copyright © 2022 Ung, Belanger, Hashmi, Sekar, Meola and Chang.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Timothy H Ung (TH)

Department of Neurosurgery, Stanford University, Palo Alto, CA, United States.
Department of Neurosurgery, University of Colorado School of Medicine, Aurora, CO, United States.

Katherine Belanger (K)

Department of Neurosurgery, University of Colorado School of Medicine, Aurora, CO, United States.

Ayesha Hashmi (A)

Department of Neurosurgery, Stanford University, Palo Alto, CA, United States.

Vashisht Sekar (V)

Department of Neurosurgery, Stanford University, Palo Alto, CA, United States.

Antonio Meola (A)

Department of Neurosurgery, Stanford University, Palo Alto, CA, United States.

Steven D Chang (SD)

Department of Neurosurgery, Stanford University, Palo Alto, CA, United States.

Classifications MeSH