Mucorales PCR in blood as an early marker of invasive gastrointestinal mucormycosis might decrease the delay in treatment: A case report.
Critically ill patient
Invasive mould infections
Mucorales PCR
Mucormycosis
Opportunistic infections
Journal
Medical mycology case reports
ISSN: 2211-7539
Titre abrégé: Med Mycol Case Rep
Pays: Netherlands
ID NLM: 101598259
Informations de publication
Date de publication:
Mar 2023
Mar 2023
Historique:
received:
23
11
2022
revised:
08
12
2022
accepted:
08
12
2022
entrez:
2
1
2023
pubmed:
3
1
2023
medline:
3
1
2023
Statut:
epublish
Résumé
We describe the fatal case of a patient with gastric perforation due to ischemia and necrosis of the stomach secondary to generalized vascular thrombosis following allogeneic hematopoietic cell transplantation. Histopathological examination of the resected stomach, spleen and omentum unexpectedly showed fungal hyphae suggestive of invasive mucormycosis. We retrospectively performed Mucorales PCR (MucorGenius®, PathoNostics, Maastricht, The Netherlands) in blood and tissue samples of this patient. The PCR was positive 16 days before time of death and 9 days before abdominal pain.
Identifiants
pubmed: 36590367
doi: 10.1016/j.mmcr.2022.12.001
pii: S2211-7539(22)00045-8
pmc: PMC9794765
doi:
Types de publication
Case Reports
Langues
eng
Pagination
8-12Informations de copyright
© 2022 The Authors.
Déclaration de conflit d'intérêts
The authors declare that there are no conflicts of interest.
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