Prolonged waitlisting is associated with mortality in extracorporeal membrane oxygenation-supported heart transplantation candidates.
BMI, body mass index
ECMO, extracorporeal membrane oxygenation
HR, hazard ratio
HTx, heart transplantation
IABP, intra-aortic balloon pump
IQR, interquartile range
LVAD, left ventricular assist device
OR, odds ratio
SRTR, Scientific Registry of Transplant Recipients
allocation system
heart transplantation
prolonged waitlisting
Journal
JTCVS open
ISSN: 2666-2736
Titre abrégé: JTCVS Open
Pays: Netherlands
ID NLM: 101768541
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
17
05
2022
revised:
07
09
2022
accepted:
21
09
2022
entrez:
2
1
2023
pubmed:
3
1
2023
medline:
3
1
2023
Statut:
epublish
Résumé
Heart transplantation (HTx) candidates supported with venoarterial extracorporeal membrane oxygenation (ECMO) may be listed at highest status 1 but are at inherent risk for ECMO-related complications. The effect of waitlist time on postlisting survival remains unclear in candidates with ECMO support who are listed using the new allocation system. Adult candidates listed with ECMO for a first-time, single-organ HTx from October 18, 2018, to March 21, 2021, in the Scientific Registry of Transplant Recipients database were included and stratified according to waitlist time (≤7 vs ≥8 days). Postlisting outcomes were compared between cohorts. Among 175 candidates waitlisted for ≤7 days, 162 (92.6%) underwent HTx whereas 13 (7.4%) died/deteriorated compared with 41 (57.8%) and 21 (29.6%) of the 71 candidates waitlisted for ≥8 days, respectively ( Among ECMO-supported candidates, obtaining HTx within 1 week of listing might improve overall survival.
Identifiants
pubmed: 36590718
doi: 10.1016/j.xjon.2022.09.010
pii: S2666-2736(22)00363-1
pmc: PMC9801284
doi:
Types de publication
Journal Article
Langues
eng
Pagination
234-254Informations de copyright
© 2022 The Author(s).
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