Combined use of coenzyme Q10 and citicoline: A new possibility for patients with glaucoma.
citicoline
coenzyme Q10 (CoQ10)
glaucoma
neuroprotection
retinal ganglion cell death
Journal
Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047
Informations de publication
Date de publication:
2022
2022
Historique:
received:
16
08
2022
accepted:
28
11
2022
entrez:
2
1
2023
pubmed:
3
1
2023
medline:
3
1
2023
Statut:
epublish
Résumé
Glaucoma is the leading cause of irreversible blindness worldwide. Several risk factors have been involved in the pathogenesis of the disease. By now, the main treatable risk factor is elevated intraocular pressure. Nevertheless, some patients, whose intraocular pressure is considered in the target level, still experience a progression of the disease. Glaucoma is a form of multifactorial ocular neurodegeneration with complex etiology, pathogenesis, and pathology. New evidence strongly suggests brain involvement in all aspects of this disease. This hypothesis and the need to prevent glaucomatous progression led to a growing interest in the pharmacological research of new neuroprotective, non-IOP-lowering, agents. The aim of this paper is to report evidence of the usefulness of Coenzyme Q10 and Citicoline, eventually combined, in the prevention of glaucomatous neurodegeneration.
Identifiants
pubmed: 36590976
doi: 10.3389/fmed.2022.1020993
pmc: PMC9797721
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1020993Informations de copyright
Copyright © 2022 Martucci, Mancino, Cesareo, Pinazo-Duran and Nucci.
Déclaration de conflit d'intérêts
AM was medical consultant for Visufarma S.p.A. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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