Burkitt lymphoma risk shows geographic and temporal associations with


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
10 01 2023
Historique:
entrez: 3 1 2023
pubmed: 4 1 2023
medline: 6 1 2023
Statut: ppublish

Résumé

Endemic Burkitt lymphoma (eBL) is a pediatric cancer coendemic with malaria in sub-Saharan Africa, suggesting an etiological link between them. However, previous cross-sectional studies of limited geographic areas have not found a convincing association. We used spatially detailed data from the Epidemiology of Burkitt Lymphoma in East African Children and Minors (EMBLEM) study to assess this relationship. EMBLEM is a case-control study of eBL from 2010 through 2016 in six regions of Kenya, Uganda, and Tanzania. To measure the intensity of exposure to the malaria parasite,

Identifiants

pubmed: 36595676
doi: 10.1073/pnas.2211055120
pmc: PMC9926229
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Intramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2211055120

Subventions

Organisme : NCI NIH HHS
ID : HHSN261201100063C
Pays : United States
Organisme : NCI NIH HHS
ID : HHSN261201100007I
Pays : United States

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Auteurs

Kelly Broen (K)

Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109.
Center for Social Epidemiology and Population Health, School of Public Health, University of Michigan, Ann Arbor, MI 48109.

Joey Dickens (J)

Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109.
Center for Social Epidemiology and Population Health, School of Public Health, University of Michigan, Ann Arbor, MI 48109.

Rob Trangucci (R)

Department of Statistics, University of Michigan, Ann Arbor, MI 48109.

Martin D Ogwang (MD)

EMBLEM Study, St. Mary's Hospital, Lacor, Gulu.
African Field Epidemiology Network, Kampala, Uganda.

Constance N Tenge (CN)

EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya.
Academic Model Providing Access To Healthcare, Eldoret, Kenya.

Nestory Masalu (N)

EMBLEM Study, Bugando Medical Center, Mwanza, Tanzania.

Steven J Reynolds (SJ)

Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.

Esther Kawira (E)

Epidemiology of Burkitt Lymphoma in East-African Children and Minors (EMBLEM) Study, Shirati Health and Educational Foundation, Shirati, Tanzania.

Patrick Kerchan (P)

African Field Epidemiology Network, Kampala, Uganda.
EMBLEM Study, Kuluva Hospital, Arua, Uganda.

Pamela A Were (PA)

EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya.
Academic Model Providing Access To Healthcare, Eldoret, Kenya.

Robert T Kuremu (RT)

EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya.
Academic Model Providing Access To Healthcare, Eldoret, Kenya.

Walter N Wekesa (WN)

EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya.
Academic Model Providing Access To Healthcare, Eldoret, Kenya.

Tobias Kinyera (T)

EMBLEM Study, St. Mary's Hospital, Lacor, Gulu.
African Field Epidemiology Network, Kampala, Uganda.

Isaac Otim (I)

EMBLEM Study, St. Mary's Hospital, Lacor, Gulu.
African Field Epidemiology Network, Kampala, Uganda.

Ismail D Legason (ID)

African Field Epidemiology Network, Kampala, Uganda.
EMBLEM Study, Kuluva Hospital, Arua, Uganda.

Hadija Nabalende (H)

EMBLEM Study, St. Mary's Hospital, Lacor, Gulu.
African Field Epidemiology Network, Kampala, Uganda.

Ian D Buller (ID)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

Leona W Ayers (LW)

Department of Pathology,The Ohio State University, Columbus, OH 43210.

Kishor Bhatia (K)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

Robert J Biggar (RJ)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

James J Goedert (JJ)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

Mark L Wilson (ML)

Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109.

Sam M Mbulaiteye (SM)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

Jon Zelner (J)

Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109.
Center for Social Epidemiology and Population Health, School of Public Health, University of Michigan, Ann Arbor, MI 48109.

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