Associations Between Muscle Weakness and Clinical Outcomes in Current and Former Smokers.
COPD outcomes
COPDGene
chronic obstructive pulmonary disease
cigarette smoking
musculoskeletal comorbidities
Journal
Chronic obstructive pulmonary diseases (Miami, Fla.)
ISSN: 2372-952X
Titre abrégé: Chronic Obstr Pulm Dis
Pays: United States
ID NLM: 101635411
Informations de publication
Date de publication:
25 Jan 2023
25 Jan 2023
Historique:
pubmed:
5
1
2023
medline:
5
1
2023
entrez:
4
1
2023
Statut:
ppublish
Résumé
Smokers with chronic obstructive pulmonary disease (COPD) are at increased risk of muscle weakness. There are limited data describing weakness in smokers with normal spirometry and preserved ratio-impaired spirometry (PRISm), 2 subgroups at risk of respiratory symptom burden and activity limitations. In this study, we evaluated the associations of 2 weakness measures, sit-to-stand (STS) and handgrip strength (HGS), with clinical outcomes in smokers with COPD, normal spirometry, and PRISm. We evaluated 1972 current and former smokers from the COPD Genetic Epidemiology (COPDGene Compared with HGS, STS was more strongly associated with the 6MWD (β=0.45, STS and HGS are easy to perform weakness measures that provide important information about functional performance, health-related quality of life, severe exacerbations, and survival in smokers, regardless of spirometric subgroup. This iterates the importance of screening current and former smokers for weakness in the outpatient setting.
Identifiants
pubmed: 36599111
doi: 10.15326/jcopdf.2022.0365
pmc: PMC9995230
doi:
Types de publication
Journal Article
Langues
eng
Pagination
112-121Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL153460
Pays : United States
Organisme : NHLBI NIH HHS
ID : F32 HL164309
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL089856
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL007563
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL089897
Pays : United States
Informations de copyright
JCOPDF © 2023.
Références
J Am Geriatr Soc. 2002 May;50(5):889-96
pubmed: 12028177
Am J Respir Crit Care Med. 2018 Dec 1;198(11):1397-1405
pubmed: 29874098
J Thorac Dis. 2018 Aug;10(8):5086-5099
pubmed: 30233884
Respir Med. 2017 Jul;128:70-77
pubmed: 28610673
Eur Respir J. 2013 Oct;42(4):956-63
pubmed: 23520321
Am J Respir Crit Care Med. 2002 Jul 1;166(1):111-7
pubmed: 12091180
Int J Chron Obstruct Pulmon Dis. 2017 Aug 09;12:2385-2390
pubmed: 28848339
Eur Respir J. 2009 Sep;34(3):648-54
pubmed: 19720809
Eur Respir J. 1997 Feb;10(2):417-23
pubmed: 9042643
Am J Respir Crit Care Med. 2017 Jan 1;195(1):17-22
pubmed: 27598473
Lancet Respir Med. 2022 Feb;10(2):149-157
pubmed: 34739861
Eur Respir J. 2008 Mar;31(3):492-501
pubmed: 18310396
Am J Respir Crit Care Med. 1995 Aug;152(2):653-7
pubmed: 7633722
Respir Res. 2014 Aug 06;15:89
pubmed: 25096860
COPD. 2005 Mar;2(1):75-9
pubmed: 17136966
Ann Am Thorac Soc. 2017 Nov;14(11):1638-1645
pubmed: 29090990
Thorax. 2010 Jun;65(6):499-504
pubmed: 20522846
Thorax. 2006 Jan;61(1):10-6
pubmed: 16284220
Chest. 2015 Oct;148(4):986-994
pubmed: 25996450
N Engl J Med. 2016 May 12;374(19):1811-21
pubmed: 27168432
Respir Med. 2007 Feb;101(2):286-93
pubmed: 16806873
Respir Med. 2005 Dec;99 Suppl B:S3-10
pubmed: 16219454
J Cardiopulm Rehabil. 2000 Nov-Dec;20(6):353-60
pubmed: 11144041
Respir Res. 2016 Nov 10;17(1):147
pubmed: 27832774
Int J Chron Obstruct Pulmon Dis. 2012;7:523-35
pubmed: 22973093
Chest. 1995 Jun;107(6):1585-9
pubmed: 7781351
JAMA Intern Med. 2015 Sep;175(9):1539-49
pubmed: 26098755
Eur Respir J. 2020 Jan 2;55(1):
pubmed: 31601717
JAMA. 2003 Nov 5;290(17):2301-12
pubmed: 14600189
Eur Respir J. 2010 Jul;36(1):81-8
pubmed: 19897554
Thorax. 2021 Dec 1;:
pubmed: 34853157
Thorax. 2006 Jan;61(1):1-3
pubmed: 16396949
J Cachexia Sarcopenia Muscle. 2011 Jun;2(2):81-86
pubmed: 21766053
Respir Res. 2017 Jun 2;18(1):112
pubmed: 28578705
Am J Respir Crit Care Med. 1996 Mar;153(3):976-80
pubmed: 8630582
COPD. 2010 Feb;7(1):32-43
pubmed: 20214461
Am J Respir Crit Care Med. 1998 Aug;158(2):629-34
pubmed: 9700144
Acta Diabetol. 2018 Feb;55(2):155-164
pubmed: 29185052