Overview of Ancillary Techniques in Cervical Cytology.

Female Humans Uterine Cervical Neoplasms / diagnosis Uterine Cervical Dysplasia Ki-67 Antigen Papillomavirus Infections / diagnosis Early Detection of Cancer / methods Cyclin-Dependent Kinase Inhibitor p16
Cervical screening Dual staining Genotyping High-risk HPV Methylation

Journal

Acta cytologica
ISSN: 1938-2650
Titre abrégé: Acta Cytol
Pays: Switzerland
ID NLM: 0370307

Informations de publication

Date de publication:
2023
Historique:
received: 22 11 2022
accepted: 23 12 2022
medline: 31 3 2023
pubmed: 5 1 2023
entrez: 4 1 2023
Statut: ppublish

Résumé

The association between high-risk serotypes of human papillomavirus (hr-HPV) and cervical cancer is well-established. In order to improve the sensitivity of cervical cytology testing, hr-HPV testing has rapidly become part of routine cervical cancer screening, either in conjunction with cytology or as primary testing. In this review, we discuss the overall utility and strategies of hr-HPV testing, as well as the advantages and limitations of potential triage strategies for hr-HPV-positive women, including HPV genotyping, p16/Ki-67 dual staining, and methylation assays. hr-HPV testing is discussed as primary screening and HPV genotyping, p16/Ki-67 dual staining, and methylation assays are discussed as ancillary techniques to cytology in the triage of hr-HPV-positive women undergoing cervical cancer screening.

Sections du résumé

BACKGROUND BACKGROUND
The association between high-risk serotypes of human papillomavirus (hr-HPV) and cervical cancer is well-established.
SUMMARY CONCLUSIONS
In order to improve the sensitivity of cervical cytology testing, hr-HPV testing has rapidly become part of routine cervical cancer screening, either in conjunction with cytology or as primary testing. In this review, we discuss the overall utility and strategies of hr-HPV testing, as well as the advantages and limitations of potential triage strategies for hr-HPV-positive women, including HPV genotyping, p16/Ki-67 dual staining, and methylation assays.
KEY MESSAGE CONCLUSIONS
hr-HPV testing is discussed as primary screening and HPV genotyping, p16/Ki-67 dual staining, and methylation assays are discussed as ancillary techniques to cytology in the triage of hr-HPV-positive women undergoing cervical cancer screening.

Identifiants

DOI: 10.1159/000528931 PMID: 36599328
pubmed: 36599328
pii: 000528931
doi: 10.1159/000528931
doi:

Substances chimiques

Ki-67 Antigen 0
Cyclin-Dependent Kinase Inhibitor p16 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

119-128

Informations de copyright

© 2023 S. Karger AG, Basel.

Auteurs

Andrea D Olivas (AD)

Department of Pathology, University of Chicago Medicine, Chicago, Illinois, USA.

Julieta E Barroeta (JE)

Department of Pathology, Cooper University Hospital, Camden, New Jersey, USA.

Ricardo R Lastra (RR)

Department of Pathology, University of Chicago Medicine, Chicago, Illinois, USA.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Overview of Ancillary Techniques in Cervical Cytology.
questionsmedicales.fr › Maladies urogénitales › Tumeurs de l'appareil urogénital › Tumeurs de l'appareil génital féminin › Tumeurs de l'utérus › Tumeurs du col de l'utérus › Overview of Ancillary Techniques in Cervical Cytology.
questionsmedicales.fr › Maladies urogénitales › Maladies génitales › Maladies de l'appareil génital féminin › Maladies de l'utérus › Maladies du col utérin › Dysplasie du col utérin › Overview of Ancillary Techniques in Cervical Cytology.
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Marqueurs biologiques tumoraux › Antigène KI-67 › Overview of Ancillary Techniques in Cervical Cytology.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladies transmissibles › Maladies sexuellement transmissibles › Maladies sexuellement transmissibles virales › Infections à papillomavirus › Overview of Ancillary Techniques in Cervical Cytology.
questionsmedicales.fr › Diagnostic › Diagnostic précoce › Dépistage précoce du cancer › Overview of Ancillary Techniques in Cervical Cytology.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines tumorales › Protéines suppresseurs de tumeurs › Protéines inhibitrices des kinases cyclines-dépendantes › Inhibiteur p16 de kinase cycline-dépendante › Overview of Ancillary Techniques in Cervical Cytology.