Does the trained immune system play an important role in the extreme longevity that is seen in the Sardinian blue zone?
Italy
Sardinia
infection
lifestyle
longevity blue zone
trained immunity
Journal
Frontiers in aging
ISSN: 2673-6217
Titre abrégé: Front Aging
Pays: Switzerland
ID NLM: 9918231199706676
Informations de publication
Date de publication:
2022
2022
Historique:
received:
13
10
2022
accepted:
06
12
2022
entrez:
5
1
2023
pubmed:
6
1
2023
medline:
6
1
2023
Statut:
epublish
Résumé
Villages in the island of Sardinia in the Mediterranean that display exceptional longevity are clustered within a defined mountainous region. Because of their unique location we hypothesize that these villages had a unique infectious disease exposure relevant to the observed successful longevity. These highland villages had a significant exposure to malaria in the first half of the 20th century after which malaria was eliminated due to vector control mechanisms. In addition, there is likely a high incidence of
Identifiants
pubmed: 36601618
doi: 10.3389/fragi.2022.1069415
pii: 1069415
pmc: PMC9806115
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1069415Informations de copyright
Copyright © 2022 Soloski, Poulain and Pes.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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