Efficacy of endoscopy under general anesthesia for the detection of synchronous lesions in oro-hypopharyngeal cancer.
Anesthesia, General
Squamous cell carcinoma of the head and neck
Transoral surgery
Journal
Clinical endoscopy
ISSN: 2234-2400
Titre abrégé: Clin Endosc
Pays: Korea (South)
ID NLM: 101576886
Informations de publication
Date de publication:
May 2023
May 2023
Historique:
received:
03
02
2022
accepted:
19
04
2022
medline:
6
1
2023
pubmed:
6
1
2023
entrez:
5
1
2023
Statut:
ppublish
Résumé
Image-enhanced endoscopy can detect superficial oro-hypopharyngeal squamous cell carcinoma; however, reliable endoscopy of the pharyngeal region is challenging. Endoscopy under general anesthesia during transoral surgery occasionally reveals multiple synchronous lesions that remained undetected on preoperative endoscopy. Therefore, we aimed to determine the lesion detection capability of endoscopy under general anesthesia for superficial oro-hypopharyngeal squamous cell carcinoma. This retrospective study included 63 patients who underwent transoral surgery for superficial oropharyngeal squamous cell carcinoma between April 2005 and December 2020. The primary endpoint was to compare the lesion detection capabilities of preoperative endoscopy and endoscopy under general anesthesia. Other endpoints included the comparison of clinicopathological findings between lesions detected using preoperative endoscopy and those newly detected using endoscopy under general anesthesia. Fifty-eight patients (85 lesions) were analyzed. The mean number of lesions per patient detected was 1.17 for preoperative endoscopy and 1.47 for endoscopy under general anesthesia. Endoscopy under general anesthesia helped detect more lesions than preoperative endoscopy did (p<0.001). The lesions that were newly detected on endoscopy under general anesthesia were small and characterized by few changes in color and surface ruggedness. Endoscopy under general anesthesia for superficial squamous cell carcinoma is helpful for detecting multiple synchronous lesions.
Sections du résumé
BACKGROUND/AIMS
OBJECTIVE
Image-enhanced endoscopy can detect superficial oro-hypopharyngeal squamous cell carcinoma; however, reliable endoscopy of the pharyngeal region is challenging. Endoscopy under general anesthesia during transoral surgery occasionally reveals multiple synchronous lesions that remained undetected on preoperative endoscopy. Therefore, we aimed to determine the lesion detection capability of endoscopy under general anesthesia for superficial oro-hypopharyngeal squamous cell carcinoma.
METHODS
METHODS
This retrospective study included 63 patients who underwent transoral surgery for superficial oropharyngeal squamous cell carcinoma between April 2005 and December 2020. The primary endpoint was to compare the lesion detection capabilities of preoperative endoscopy and endoscopy under general anesthesia. Other endpoints included the comparison of clinicopathological findings between lesions detected using preoperative endoscopy and those newly detected using endoscopy under general anesthesia.
RESULTS
RESULTS
Fifty-eight patients (85 lesions) were analyzed. The mean number of lesions per patient detected was 1.17 for preoperative endoscopy and 1.47 for endoscopy under general anesthesia. Endoscopy under general anesthesia helped detect more lesions than preoperative endoscopy did (p<0.001). The lesions that were newly detected on endoscopy under general anesthesia were small and characterized by few changes in color and surface ruggedness.
CONCLUSION
CONCLUSIONS
Endoscopy under general anesthesia for superficial squamous cell carcinoma is helpful for detecting multiple synchronous lesions.
Identifiants
pubmed: 36601670
pii: ce.2022.072
doi: 10.5946/ce.2022.072
pmc: PMC10244144
doi:
Types de publication
Journal Article
Langues
eng
Pagination
315-324Commentaires et corrections
Type : CommentIn
Références
Gastrointest Endosc. 2015 Dec;82(6):1002-8
pubmed: 26234696
Head Neck. 1998 Dec;20(8):714-9
pubmed: 9790293
Cancer Med. 2021 Jun;10(12):3848-3861
pubmed: 33991076
J Am Coll Surg. 2005 Aug;201(2):188-93
pubmed: 16038814
J Clin Oncol. 2003 Dec 1;21(23):4336-41
pubmed: 14645422
Cancer. 2004 Sep 15;101(6):1375-81
pubmed: 15368325
Cancer. 1953 Sep;6(5):963-8
pubmed: 13094644
J Gastroenterol Hepatol. 2008 Apr;23(4):546-50
pubmed: 17573830
Oncol Res Treat. 2017;40(9):503-506
pubmed: 28848123
World J Gastroenterol. 2017 Feb 14;23(6):1051-1058
pubmed: 28246479
World J Gastroenterol. 2013 Jul 21;19(27):4300-8
pubmed: 23885140
Auris Nasus Larynx. 2021 Jun;48(3):457-463
pubmed: 33067052
Surg Endosc. 1992 Sep-Oct;6(5):264-5
pubmed: 1465738
Laryngoscope. 2005 May;115(5):864-9
pubmed: 15867655
Gastrointest Endosc. 2011 Sep;74(3):477-84
pubmed: 21704994
Int J Radiat Oncol Biol Phys. 2001 Mar 15;49(4):907-16
pubmed: 11240231
Endosc Int Open. 2015 Aug;3(4):E266-73
pubmed: 26357670
J Clin Oncol. 2010 Mar 20;28(9):1566-72
pubmed: 20177025
Dig Endosc. 2017 Jan;29(1):39-48
pubmed: 27696551