Unmasking lower gastrointestinal bleeding under administration of norepinephrine.
Endoscopy
Gastrointestinal bleeding
Lower gastrointestinal bleeding
Norepinephrine
Provocative angiography
Radiology
Journal
World journal of radiology
ISSN: 1949-8470
Titre abrégé: World J Radiol
Pays: United States
ID NLM: 101538184
Informations de publication
Date de publication:
28 Dec 2022
28 Dec 2022
Historique:
received:
09
09
2022
revised:
24
10
2022
accepted:
01
12
2022
entrez:
6
1
2023
pubmed:
7
1
2023
medline:
7
1
2023
Statut:
ppublish
Résumé
Bleeding in the gastrointestinal tract is common and transarterial embolization enables the clinician to control gastrointestinal bleeding. Contrast extravasation is a prerequisite for successful embolization. Provocative angiography is helpful in the detection of elusive bleeding. We performed a retrospective analysis of angiographic treatment in patients with lower gastrointestinal hemorrhage and initially negative angiographies, as well as the role of norepinephrine (NE) in unmasking bleeding. We analyzed 41 patients with lower gastrointestinal bleeding after angiography who had undergone treatment over a period of 10 years. All patients had a positive shock index and needed intensive care. In three of four patients, angiography disclosed the site of bleeding when NE was used during the procedure for hemodynamic stabilization. We suggest that angiography performed after the administration of NE in unstable patients with gastrointestinal bleeding and an initially negative angiography has the potential to unmask bleeding sites for successful embolization. However, this statement must be confirmed in prospective studies.
Sections du résumé
BACKGROUND
BACKGROUND
Bleeding in the gastrointestinal tract is common and transarterial embolization enables the clinician to control gastrointestinal bleeding. Contrast extravasation is a prerequisite for successful embolization. Provocative angiography is helpful in the detection of elusive bleeding.
AIM
OBJECTIVE
We performed a retrospective analysis of angiographic treatment in patients with lower gastrointestinal hemorrhage and initially negative angiographies, as well as the role of norepinephrine (NE) in unmasking bleeding.
METHODS
METHODS
We analyzed 41 patients with lower gastrointestinal bleeding after angiography who had undergone treatment over a period of 10 years. All patients had a positive shock index and needed intensive care.
RESULTS
RESULTS
In three of four patients, angiography disclosed the site of bleeding when NE was used during the procedure for hemodynamic stabilization.
CONCLUSION
CONCLUSIONS
We suggest that angiography performed after the administration of NE in unstable patients with gastrointestinal bleeding and an initially negative angiography has the potential to unmask bleeding sites for successful embolization. However, this statement must be confirmed in prospective studies.
Identifiants
pubmed: 36605886
doi: 10.4329/wjr.v14.i12.375
pmc: PMC9808013
doi:
Types de publication
Journal Article
Langues
eng
Pagination
375-383Informations de copyright
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflict-of-interest statement: All authors declare that they have no conflicts of interest.