Unmasking lower gastrointestinal bleeding under administration of norepinephrine.

Endoscopy Gastrointestinal bleeding Lower gastrointestinal bleeding Norepinephrine Provocative angiography Radiology

Journal

World journal of radiology
ISSN: 1949-8470
Titre abrégé: World J Radiol
Pays: United States
ID NLM: 101538184

Informations de publication

Date de publication:
28 Dec 2022
Historique:
received: 09 09 2022
revised: 24 10 2022
accepted: 01 12 2022
entrez: 6 1 2023
pubmed: 7 1 2023
medline: 7 1 2023
Statut: ppublish

Résumé

Bleeding in the gastrointestinal tract is common and transarterial embolization enables the clinician to control gastrointestinal bleeding. Contrast extravasation is a prerequisite for successful embolization. Provocative angiography is helpful in the detection of elusive bleeding. We performed a retrospective analysis of angiographic treatment in patients with lower gastrointestinal hemorrhage and initially negative angiographies, as well as the role of norepinephrine (NE) in unmasking bleeding. We analyzed 41 patients with lower gastrointestinal bleeding after angiography who had undergone treatment over a period of 10 years. All patients had a positive shock index and needed intensive care. In three of four patients, angiography disclosed the site of bleeding when NE was used during the procedure for hemodynamic stabilization. We suggest that angiography performed after the administration of NE in unstable patients with gastrointestinal bleeding and an initially negative angiography has the potential to unmask bleeding sites for successful embolization. However, this statement must be confirmed in prospective studies.

Sections du résumé

BACKGROUND BACKGROUND
Bleeding in the gastrointestinal tract is common and transarterial embolization enables the clinician to control gastrointestinal bleeding. Contrast extravasation is a prerequisite for successful embolization. Provocative angiography is helpful in the detection of elusive bleeding.
AIM OBJECTIVE
We performed a retrospective analysis of angiographic treatment in patients with lower gastrointestinal hemorrhage and initially negative angiographies, as well as the role of norepinephrine (NE) in unmasking bleeding.
METHODS METHODS
We analyzed 41 patients with lower gastrointestinal bleeding after angiography who had undergone treatment over a period of 10 years. All patients had a positive shock index and needed intensive care.
RESULTS RESULTS
In three of four patients, angiography disclosed the site of bleeding when NE was used during the procedure for hemodynamic stabilization.
CONCLUSION CONCLUSIONS
We suggest that angiography performed after the administration of NE in unstable patients with gastrointestinal bleeding and an initially negative angiography has the potential to unmask bleeding sites for successful embolization. However, this statement must be confirmed in prospective studies.

Identifiants

pubmed: 36605886
doi: 10.4329/wjr.v14.i12.375
pmc: PMC9808013
doi:

Types de publication

Journal Article

Langues

eng

Pagination

375-383

Informations de copyright

©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict-of-interest statement: All authors declare that they have no conflicts of interest.

Auteurs

David John Werner (DJ)

Department of Radiology, Helios Dr. Horst-Schmidt-Clinic, Wiesbaden 65199, Hessen, Germany.
Radiologie Rhein-Nahe, Krankenhaus St. Marienwörth, Bad Kreuznach 55543, Rheinland-Pfalz, Germany.

Nicolai Wenzel (N)

Department of Radiology, Helios Dr. Horst-Schmidt-Clinic, Wiesbaden 65199, Hessen, Germany.

Nael Abusalim (N)

Department of Radiology, Helios Dr. Horst-Schmidt-Clinic, Wiesbaden 65199, Hessen, Germany.
Department of Diagnostic and Interventional Radiology, Medical Center Hanau, Hanau 63450, Hessen, Germany.

Ralf Kiesslich (R)

Department of Internal Medicine II, Helios Dr. Horst-Schmidt-Clinic, Wiesbaden 65199, Hessen, Germany.

Till Baar (T)

Institute for Medical Statistics and Computational Biology, Faculty of Medicine, University of Cologne, Cologne 50923, Nordrhein-Westfalen, Germany.

Achim Tresch (A)

Institute for Medical Statistics and Computational Biology, Faculty of Medicine, University of Cologne, Cologne 50923, Nordrhein-Westfalen, Germany.

Johannes Wilhelm Rey (JW)

Department of Internal Medicine II, Helios Dr. Horst-Schmidt-Clinic, Wiesbaden 65199, Hessen, Germany.
Department of Gastroenterology and Endoscopy, Medical Center Osnabrueck, Osnabrueck 49076, Niedersachsen, Germany. johannes.wilhelm.rey@t-online.de.

Classifications MeSH