Platelet-rich fibrin vs. buccal advancement flap for closure of oroantral communications: a prospective clinical study.
Buccal advancement
Closure of oroantral communications
Healing
Lukas Postl and Danilo-Marc Nadalini contributed equally to this work.
Mucogingival border
Platelet-rich fibrin
Journal
Clinical oral investigations
ISSN: 1436-3771
Titre abrégé: Clin Oral Investig
Pays: Germany
ID NLM: 9707115
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
received:
06
10
2022
accepted:
26
12
2022
medline:
15
6
2023
pubmed:
7
1
2023
entrez:
6
1
2023
Statut:
ppublish
Résumé
The primary aim was to evaluate the success of the defect closure (tight or open) of oroantral communications (OAC) after treatment with platelet-rich fibrin (PRF) clots or a buccal advancement flap (BAF). Secondary outcome measurements were the evaluation of the wound healing, the displacement of the mucogingival border (MGB), and the pain level. Fifty eligible patients with an OAC defect larger than 3 mm were randomly assigned to either PRF (test group, n = 25) or BAF (control group, n = 25) for defect closure. In a prospective follow-up program of 21 days, the defect closure healing process, the wound healing course using Landry's wound healing index (score: 0-5), the displacement of the MGB, and the postoperative pain score were evaluated. Five patients in each group were lost to follow-up resulting in 40 patients (20 in each group) for continuous evaluation. On postoperative day 21 (study endpoint), no difference regarding success rate (defined as closure of OAC) was noticed between the test (90%; 18/20) and control group (90%; 18/20). A univariate analysis showed significant differences for age and defect size/height for the use of PRF between successful-tight and open-failed defect healing. At the final evaluation, a significantly (p = 0.005) better wound healing score, a lower displacement of the MGB as well as lower pain-score were seen for the use of PRF. Based on the findings of the current study, the use of platelet-rich fibrin represents a reliable and successful method for closure of oroantral communications. The use of PRF clots for defect filling is associated with lowered pain levels and less displacement of the mucogingival border. The defect size should be taken into account when choosing the number and size of PRF plugs.
Identifiants
pubmed: 36607489
doi: 10.1007/s00784-022-04846-7
pii: 10.1007/s00784-022-04846-7
pmc: PMC10264294
doi:
Types de publication
Randomized Controlled Trial
Journal Article
Langues
eng
Pagination
2713-2724Informations de copyright
© 2023. The Author(s).
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