Effect of high-intensity interval walking on microvascular endothelial function among community-dwelling older people.
atherosclerosis
high-intensity interval training
nonrandomized controlled trial
sex differences
vascular endothelium
Journal
Geriatrics & gerontology international
ISSN: 1447-0594
Titre abrégé: Geriatr Gerontol Int
Pays: Japan
ID NLM: 101135738
Informations de publication
Date de publication:
Feb 2023
Feb 2023
Historique:
revised:
25
10
2022
received:
12
05
2022
accepted:
09
12
2022
pubmed:
8
1
2023
medline:
4
2
2023
entrez:
7
1
2023
Statut:
ppublish
Résumé
To investigate the effects of high-intensity interval exercise training on microvascular endothelial function among community-dwelling older people. We analyzed the data from a nonrandomized controlled trial. This study's participants were 48 men (aged 75 ± 5 years; exercise training group, n = 24; control group, n = 24) and 83 women (aged 75 ± 4 years; exercise training group, n = 36; control group, n = 47). The exercise training group underwent a high-intensity interval walking training for 5 months. In the exercise group, 100% and 91.7% of men and women, respectively, achieved brisk walking times ≥50 min/week. The change in the reactive hyperemia index significantly differed between the groups of men, whereas that in the control group was not significant; however, a significant increase was observed in the exercise training group. Among women, changes in the reactive hyperemia index were not significant in either group; however, for women in the exercise training group, these changes negatively and positively correlated with the change in body mass index (Spearman's rho = -0.342; P = 0.041) and baseline body mass index (rho = 0.362, P = 0.030), respectively. Additionally, the distribution of body mass index was broader in women than in men. Interval walking training increased the reactive hyperemia index in men rather than in women. A higher variation in baseline body mass index may be associated with no statistical increase in reactive hyperemia index in women. Geriatr Gerontol Int 2023; 23: 103-110.
Types de publication
Controlled Clinical Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
103-110Subventions
Organisme : Descente and Ishimoto Memorial Foundation for the Promotion of Sports Science
ID : Research grant
Organisme : Ministry of Education, Culture, Sports, Science and Technology
ID : the Private University Research Branding Project
Informations de copyright
© 2023 Japan Geriatrics Society.
Références
Tomiyama H, Ishizu T, Kohro T et al. Longitudinal association among endothelial function, arterial stiffness and subclinical organ damage in hypertension. Int J Cardiol 2018; 253: 161-166.
Libby P, Ridker PM, Maseri A. Inflammation and atherosclerosis. Circulation 2002; 105: 1135-1143.
Kuvin JT, Patel AR, Sliney KA et al. Assessment of peripheral vascular endothelial function with finger arterial pulse wave amplitude. Am Heart J 2003; 146: 168-174.
Ashor AW, Lara J, Siervo M et al. Exercise modalities and endothelial function: a systematic review and dose-response meta-analysis of randomized controlled trials. Sports Med 2015; 45: 279-296.
Masuki S, Morikawa M, Nose H. Internet of things (IoT) system and field sensors for exercise intensity measurements. Compr Physiol 2020; 10: 1207-1240.
Green DJ, Jones H, Thijssen D, Cable NT, Atkinson G. Flow-mediated dilation and cardiovascular event prediction: does nitric oxide matter? Hypertension 2011; 57: 363-369.
Anderson TJ, Charbonneau F, Title LM et al. Microvascular function predicts cardiovascular events in primary prevention: long-term results from the firefighters and their endothelium (FATE) study. Circulation 2011; 123: 163-169.
Cooper LL, Wang N, Beiser AS et al. Digital peripheral arterial tonometry and cardiovascular disease events: the Framingham heart study. Stroke 2021; 52: 2866-2873.
Hamada S, Oono A, Ishihara Y et al. Assessment of vascular autonomic function using peripheral arterial tonometry. Heart Vessels 2017; 32: 260-268.
Rytter N, Piil P, Carter H, Nyberg M, Hellsten Y, Gliemann L. Microvascular function is impaired after short-term immobilization in healthy men. Med Sci Sports Exerc 2020; 52: 2107-2116.
Pearson MJ, Smart NA. Effect of exercise training on endothelial function in heart failure patients: a systematic review meta-analysis. Int J Cardiol 2017; 231: 234-243.
Qiu S, Cai X, Yin H et al. Exercise training and endothelial function in patients with type 2 diabetes: a meta-analysis. Cardiovasc Diabetol 2018; 17: 64.
da Silva MR, Waclawovsky G, Perin L, Camboim I, Eibel B, Lehnen AM. Effects of high-intensity interval training on endothelial function, lipid profile, body composition and physical fitness in normal-weight and overweight-obese adolescents: a clinical trial. Physiol Behav 2020; 213: 112728.
Joris PJ, Zeegers MP, Mensink RP. Weight loss improves fasting flow-mediated vasodilation in adults: a meta-analysis of intervention studies. Atherosclerosis 2015; 239: 21-30.
Pierce GL, Eskurza I, Walker AE, Fay TN, Seals DR. Sex-specific effects of habitual aerobic exercise on brachial artery flow-mediated dilation in middle-aged and older adults. Clin Sci 2011; 120: 13-23.
Casey DP, Pierce GL, Howe KS, Mering MC, Braith RW. Effect of resistance training on arterial wave reflection and brachial artery reactivity in normotensive postmenopausal women. Eur J Appl Physiol 2007; 100: 403-408.
Shimizu R, Hotta K, Yamamoto S et al. Low-intensity resistance training with blood flow restriction improves vascular endothelial function and peripheral blood circulation in healthy elderly people. Eur J Appl Physiol 2016; 116: 749-757.
Laslovich S, Alvar BA, Allison M, Rauh MJ. Effects of lifestyle physical activity on vascular function in asymptomatic peripheral arterial disease. Med Sci Sports Exerc 2020; 52: 8-15.
Morikawa M, Okazaki K, Masuki S et al. Physical fitness and indices of lifestyle-related diseases before and after interval walking training in middle-aged and older males and females. Br J Sports Med 2011; 45: 216-224.
Giallauria F, Vitelli A, Maresca L et al. Exercise training improves cardiopulmonary and endothelial function in women with breast cancer: findings from the Diana-5 dietary intervention study. Intern Emerg Med 2016; 11: 183-189.
Hamburg NM, Keyes MJ, Larson MG et al. Cross-sectional relations of digital vascular function to cardiovascular risk factors in the Framingham heart study. Circulation 2008; 117: 2467-2474.
Gielen S, Schuler G, Adams V. Cardiovascular effects of exercise training: molecular mechanisms. Circulation 2010; 122: 1221-1238.
Padilla J, Harris RA, Rink LD, Wallace JP. Characterization of the brachial artery shear stress following walking exercise. Vasc Med 2008; 13: 105-111.
Hamburg NM, Palmisano J, Larson MG et al. Relation of brachial and digital measures of vascular function in the community: the Framingham heart study. Hypertens 2011; 57: 390-396.
Moreau KL, Stauffer BL, Kohrt WM, Seals DR. Essential role of estrogen for improvements in vascular endothelial function with endurance exercise in postmenopausal women. J Clin Endocrinol Metab 2013; 98: 4507-4515.
Seals DR, Nagy EE, Moreau KL. Aerobic exercise training and vascular function with ageing in healthy men and women. J Physiol 2019; 597: 4901-4914.
Nemoto K, Gen-no H, Masuki K, Okazaki K, Nose H. Effects of high-intensity interval walking training on physical fitness and blood pressure in middle-aged and older people. Mayo Clin Proc 2007; 82: 803-811.
Donnelly JE, Hill JO, Jacobsen DJ et al. Effects of a 16-month randomized controlled exercise trial on body weight and composition in young, overweight men and women: the Midwest exercise trial. Arch Intern Med 2003; 163: 1343-1350.
Pietrobelli A, Allison DB, Heshka S et al. Sexual dimorphism in the energy content of weight change. Int J Obes 2002; 26: 1339-1348.