How toxic is the COVID-19 drug azithromycin in the presence of Posidonia oceanica? Toxicokinetics and experimental approach of meiobenthic nematodes from a metallically pristine area.
Azithromycin
COVID-19 crisis
Ecotoxicity
Meiobenthic nematodes
Posidonia oceanica
Toxicokinetics
Journal
Environmental pollution (Barking, Essex : 1987)
ISSN: 1873-6424
Titre abrégé: Environ Pollut
Pays: England
ID NLM: 8804476
Informations de publication
Date de publication:
15 Feb 2023
15 Feb 2023
Historique:
received:
15
10
2022
revised:
27
12
2022
accepted:
02
01
2023
pubmed:
8
1
2023
medline:
25
1
2023
entrez:
7
1
2023
Statut:
ppublish
Résumé
The current study presents the results of an experiment carried to assess the impact of azithromycin, a COVID-19 drug, probably accumulated in marine sediments for three years, since the start of the pandemic, on benthic marine nematodes. It was explored the extent to which a common macrophyte from the Mediterranean Sea influenced the toxic impact of azithromycin on meiobenthic nematodes. Metals are known to influence toxicity of azithromycin. The nematofauna from a metallically pristine site situated in Bizerte bay, Tunisia, was exposed to two concentrations of azithromycin [i.e. 5 and 10 μg l
Identifiants
pubmed: 36608722
pii: S0269-7491(23)00009-X
doi: 10.1016/j.envpol.2023.121007
pmc: PMC9808061
pii:
doi:
Substances chimiques
Azithromycin
83905-01-5
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
121007Informations de copyright
Copyright © 2023 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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