Patient navigation for colorectal cancer screening in deprived areas: the COLONAV cluster randomized controlled trial.
Colorectal cancer screening
Complex interventions
Health inequalities
Patient navigation
Population health intervention research
Randomized control trial
Journal
BMC cancer
ISSN: 1471-2407
Titre abrégé: BMC Cancer
Pays: England
ID NLM: 100967800
Informations de publication
Date de publication:
06 Jan 2023
06 Jan 2023
Historique:
received:
13
05
2022
accepted:
29
09
2022
entrez:
7
1
2023
pubmed:
8
1
2023
medline:
11
1
2023
Statut:
epublish
Résumé
The objective of this study was to assess the effectiveness of a Patient Navigation Intervention targeting deprived patients for Colo-Rectal Cancer (CRC) screening participation. A cluster randomized controlled trial was conducted in 5 districts. Peer Lay Patient Navigators were recruited to operate in deprived areas. Eligible participants had to be between 50 and 74 years old, live in these deprived areas and receive an invitation to the nationally organized Colo-Rectal Cancer (CRC) screening during the study period. The theory-driven navigation intervention was deployed for 18 months. A population Health Intervention Research assessment method was used to assess effectiveness and context interaction. The primary criterion was screening participation at 12 months. Twenty-four thousand two hundred eighty-one individuals were included inside 40 clusters. The increase in participation in the intervention group was estimated at 23%, (ORa = 1.23, CI95% [1.07-1.41], p = 0.003). For the subgroup of individuals who participated, the time delay to participating was reduced by 26% (ORa = 0.74, CI95% [0.57-0.96], p = 0.021). Main factors modulating the effect of the intervention were: closeness of navigator profiles to the targeted population, navigators' abilities to adapt their modus operandi, and facilitating attachment structure. The ColoNav Intervention succeeded in demonstrating its effectiveness, for CRC screening. Patient Navigation should be disseminate with broader health promotion goals in order to achieve equity in health care. clinicaltrials.gov NCT02369757 24/02/2015.
Sections du résumé
BACKGROUND
BACKGROUND
The objective of this study was to assess the effectiveness of a Patient Navigation Intervention targeting deprived patients for Colo-Rectal Cancer (CRC) screening participation.
METHODS
METHODS
A cluster randomized controlled trial was conducted in 5 districts. Peer Lay Patient Navigators were recruited to operate in deprived areas. Eligible participants had to be between 50 and 74 years old, live in these deprived areas and receive an invitation to the nationally organized Colo-Rectal Cancer (CRC) screening during the study period. The theory-driven navigation intervention was deployed for 18 months. A population Health Intervention Research assessment method was used to assess effectiveness and context interaction. The primary criterion was screening participation at 12 months.
RESULTS
RESULTS
Twenty-four thousand two hundred eighty-one individuals were included inside 40 clusters. The increase in participation in the intervention group was estimated at 23%, (ORa = 1.23, CI95% [1.07-1.41], p = 0.003). For the subgroup of individuals who participated, the time delay to participating was reduced by 26% (ORa = 0.74, CI95% [0.57-0.96], p = 0.021). Main factors modulating the effect of the intervention were: closeness of navigator profiles to the targeted population, navigators' abilities to adapt their modus operandi, and facilitating attachment structure.
CONCLUSION
CONCLUSIONS
The ColoNav Intervention succeeded in demonstrating its effectiveness, for CRC screening. Patient Navigation should be disseminate with broader health promotion goals in order to achieve equity in health care.
TRIAL REGISTRATION
BACKGROUND
clinicaltrials.gov NCT02369757 24/02/2015.
Identifiants
pubmed: 36609248
doi: 10.1186/s12885-022-10169-3
pii: 10.1186/s12885-022-10169-3
pmc: PMC9817361
doi:
Banques de données
ClinicalTrials.gov
['NCT02369757']
Types de publication
Randomized Controlled Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
21Subventions
Organisme : Institut National Du Cancer
ID : NA
Organisme : Institut National Du Cancer
ID : NA
Organisme : Institut National Du Cancer
ID : NA
Organisme : Institut National Du Cancer
ID : NA
Organisme : Institut National Du Cancer
ID : NA
Organisme : Institut National Du Cancer
ID : NA
Organisme : Institut National Du Cancer
ID : NA
Organisme : Ligue Contre le Cancer
ID : NA
Informations de copyright
© 2023. The Author(s).
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