The Anti- and Pro-Tumorigenic Role of Microbiota and Its Role in Anticancer Therapeutic Strategies.
cancer
cancer therapy
genotoxicity
microbiota
probiotics
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
28 Dec 2022
28 Dec 2022
Historique:
received:
15
11
2022
revised:
22
12
2022
accepted:
23
12
2022
entrez:
8
1
2023
pubmed:
9
1
2023
medline:
9
1
2023
Statut:
epublish
Résumé
Human gut microbiota physiologically and actively participates as a symbiont to a wide number of fundamental biological processes, such as absorption and metabolism of nutrients, regulation of immune response and inflammation; gut microbiota plays also an antitumor role. However, dysbiosis, resulting from a number of different situations-dysmicrobism, infections, drug intake, age, diet-as well as from their multiple combinations, may lead to tumorigenesis and is associated with approximately 20% of all cancers. In a diagnostic, prognostic, therapeutic, and epidemiological perspective, it is clear that the bifaceted role of microbiota needs to be thoroughly studied and better understood. Here, we discuss the anti- and pro-tumorigenic potential of gut and other microbiota districts along with the causes that may change commensal bacteria from friend to foes.
Identifiants
pubmed: 36612186
pii: cancers15010190
doi: 10.3390/cancers15010190
pmc: PMC9818275
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Toxins (Basel). 2018 Apr 10;10(4):
pubmed: 29642622
Mutat Res. 2009 Nov 2;670(1-2):59-67
pubmed: 19631670
Comput Toxicol. 2021 Nov;20:
pubmed: 34901581
Genet Mol Res. 2017 Mar 22;16(1):
pubmed: 28340269
EMBO J. 2021 Jul 1;40(13):e106272
pubmed: 33942347
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2014;31(10):1678-87
pubmed: 25010287
Eur J Cancer Prev. 2003 Apr;12(2):101-7
pubmed: 12671533
Cancer Discov. 2018 Apr;8(4):403-416
pubmed: 29567829
Science. 2019 Feb 15;363(6428):
pubmed: 30765538
Clin Colorectal Cancer. 2021 Sep;20(3):e165-e172
pubmed: 33935016
Nat Neurosci. 2017 Sep;20(9):1213-1216
pubmed: 28714953
J Biol Chem. 2017 May 26;292(21):8546-8552
pubmed: 28389564
Int J Pharm. 2008 Nov 3;363(1-2):1-25
pubmed: 18682282
Cell Host Microbe. 2013 Aug 14;14(2):195-206
pubmed: 23954158
Cell. 2019 Aug 8;178(4):795-806.e12
pubmed: 31398337
Appl Environ Microbiol. 2007 Jun;73(12):3958-64
pubmed: 17449679
J Appl Microbiol. 2014 Sep;117(3):824-33
pubmed: 24849144
PLoS One. 2014 Jan 08;9(1):e83744
pubmed: 24421902
Nat Microbiol. 2016 Oct 17;2:16189
pubmed: 27748768
Gut Microbes. 2021 Jan-Dec;13(1):1979882
pubmed: 34724858
Folia Microbiol (Praha). 2019 May;64(3):435-442
pubmed: 30554379
Toxicol In Vitro. 2006 Mar;20(2):163-75
pubmed: 16271446
J Microbiol Biotechnol. 2014 Mar 28;24(3):371-8
pubmed: 24346468
Cell Host Microbe. 2008 Jan 17;3(1):30-8
pubmed: 18191792
DNA Repair (Amst). 2005 Feb 3;4(2):271-7
pubmed: 15590335
Nature. 2019 Jan;565(7741):600-605
pubmed: 30675064
J Appl Genet. 2014 May;55(2):273-85
pubmed: 24615570
Clin Cancer Res. 2016 Nov 15;22(22):5574-5581
pubmed: 27769987
Arch Surg. 2004 Jul;139(7):760-5
pubmed: 15249410
Lett Appl Microbiol. 2008 Mar;46(3):331-7
pubmed: 18194161
Cancer Prev Res (Phila). 2013 Jul;6(7):686-94
pubmed: 23658366
Clin Chim Acta. 2003 May;331(1-2):127-34
pubmed: 12691873
Genome Res. 2012 Feb;22(2):299-306
pubmed: 22009989
Gut. 2016 Dec;65(12):1973-1980
pubmed: 26311717
Front Microbiol. 2018 May 15;9:951
pubmed: 29867857
Gene. 2011 Dec 15;490(1-2):54-9
pubmed: 21963996
Mol Cancer Res. 2007 May;5(5):455-9
pubmed: 17475672
Toxins (Basel). 2011 Mar;3(3):172-90
pubmed: 22069704
Gut Microbes. 2019;10(3):398-411
pubmed: 30359553
Int J Food Microbiol. 2005 Jun 25;102(1):37-47
pubmed: 15925000
Cell Death Differ. 2021 May;28(5):1532-1547
pubmed: 33262469
J Cancer Prev. 2017 Jun;22(2):108-114
pubmed: 28698865
J Oncol. 2020 Feb 10;2020:5490468
pubmed: 32104177
Cancers (Basel). 2019 Jan 03;11(1):
pubmed: 30609850
Cell. 2016 Apr 7;165(2):276-87
pubmed: 27058662
J Microbiol Biotechnol. 2015 Oct;25(10):1680-6
pubmed: 26059518
Food Chem Toxicol. 2006 Dec;44(12):2058-63
pubmed: 16979277
Am J Clin Nutr. 2014 Jul;100 Suppl 1:386S-93S
pubmed: 24847855
Antonie Van Leeuwenhoek. 2008 Jan-Feb;93(1-2):51-9
pubmed: 17588126
Cancer Manag Res. 2022 Oct 18;14:3021-3036
pubmed: 36262751
Science. 2017 Dec 15;358(6369):1443-1448
pubmed: 29170280
PLoS One. 2018 Jan 17;13(1):e0189721
pubmed: 29342165
Cell. 2005 Dec 16;123(6):975-6
pubmed: 16360024
Cell Microbiol. 2002 Feb;4(2):87-99
pubmed: 11896765
Oncotarget. 2017 Nov 1;8(60):102176-102190
pubmed: 29254234
Appl Environ Microbiol. 2016 Jul 29;82(16):5039-48
pubmed: 27342554
Science. 2021 Mar 26;371(6536):
pubmed: 33766858
PLoS One. 2013;8(2):e56964
pubmed: 23457644
Science. 2010 Nov 5;330(6005):831-5
pubmed: 21051639
Toxicol Appl Pharmacol. 1993 Aug;121(2):233-8
pubmed: 8346540
Eur J Nutr. 2009 Oct;48(7):419-27
pubmed: 19448966
Nat Commun. 2016 Feb 02;7:10391
pubmed: 26837003
Nat Rev Microbiol. 2008 Jun;6(6):441-54
pubmed: 18461075
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2015;32(11):1927-38
pubmed: 26295367
BMC Complement Altern Med. 2017 May 5;17(1):251
pubmed: 28476162
Science. 2020 May 29;368(6494):973-980
pubmed: 32467386
Cancers (Basel). 2022 Jul 22;14(15):
pubmed: 35892821
Epidemiol Infect. 2021 Feb 08;149:e56
pubmed: 33551005
Front Microbiol. 2020 Nov 05;11:562813
pubmed: 33224110
ACS Infect Dis. 2018 Jan 12;4(1):68-76
pubmed: 29160065
Nat Chem Biol. 2022 Oct 17;:
pubmed: 36253549
Sci Total Environ. 2019 Dec 15;696:133971
pubmed: 31470323
Pharmacol Res. 2020 Mar;153:104683
pubmed: 32050092
Microbiome. 2019 Apr 25;7(1):66
pubmed: 31018870
Gastroenterology. 2003 Feb;124(2):392-400
pubmed: 12557145
EXS. 2009;99:87-110
pubmed: 19157059
Int J Biol Macromol. 2020 Nov 1;162:853-865
pubmed: 32585269
J Exp Med. 2020 May 4;217(5):
pubmed: 32142585
Anticancer Res. 2019 Nov;39(11):6265-6271
pubmed: 31704856
Front Microbiol. 2021 Dec 15;12:797445
pubmed: 34975821
PLoS One. 2017 Nov 30;12(11):e0188873
pubmed: 29190829
Int J Mol Sci. 2020 Dec 17;21(24):
pubmed: 33348640
J Pharmacol Exp Ther. 1998 Nov;287(2):791-9
pubmed: 9808711
Science. 2015 Nov 27;350(6264):1084-9
pubmed: 26541606
Cell Microbiol. 2013 Jan;15(1):1-15
pubmed: 22978660
J Dairy Sci. 2008 Aug;91(8):2960-6
pubmed: 18650272
CA Cancer J Clin. 2017 Jul 8;67(4):326-344
pubmed: 28481406
Mol Nutr Food Res. 2021 Jun;65(12):e2001149
pubmed: 33900027
Chem Biol. 2012 Oct 26;19(10):1255-64
pubmed: 23102220
Nat Rev Microbiol. 2016 Apr;14(5):273-87
pubmed: 26972811
Oxid Med Cell Longev. 2013;2013:471790
pubmed: 23533692
Sci Rep. 2015 Sep 29;5:14554
pubmed: 26416623
Int J Cancer. 2015 Sep 15;137(6):1258-68
pubmed: 25703934
World J Surg Oncol. 2014 May 24;12:164
pubmed: 24884764
Science. 2013 Nov 22;342(6161):971-6
pubmed: 24264990
Genome Biol. 2018 Aug 24;19(1):123
pubmed: 30143034
World J Gastroenterol. 2016 Jan 14;22(2):501-18
pubmed: 26811603
Nat Rev Cancer. 2016 Dec;16(12):789-802
pubmed: 27687982
Cell Metab. 2021 May 4;33(5):988-1000.e7
pubmed: 33761313
Nat Chem Biol. 2022 Oct 17;:
pubmed: 36253550
Cell. 2017 Jul 27;170(3):548-563.e16
pubmed: 28753429
Science. 2015 Nov 27;350(6264):1079-84
pubmed: 26541610
Gut Microbes. 2016 Sep 2;7(5):414-23
pubmed: 27459363
Infect Immun. 2009 Nov;77(11):4696-703
pubmed: 19720753
Cell Rep. 2018 Sep 25;24(13):3528-3538
pubmed: 30257213
Sci Adv. 2018 Feb 28;4(2):eaao4502
pubmed: 29507878
Front Microbiol. 2017 Nov 28;8:2349
pubmed: 29234315
Int J Food Microbiol. 2008 Jul 31;125(3):330-5
pubmed: 18538879
Anaerobe. 2011 Oct;17(5):217-22
pubmed: 21777684
Mutat Res. 1998 Feb 2;397(2):169-82
pubmed: 9541641
Benef Microbes. 2019 Apr 19;10(4):449-461
pubmed: 30957533
Prep Biochem Biotechnol. 2015 Aug 18;45(6):530-50
pubmed: 25036875
J Exp Clin Cancer Res. 2021 Oct 16;40(1):327
pubmed: 34656142
Gut Microbes. 2013 Jul-Aug;4(4):292-305
pubmed: 23652772
Curr Med Mycol. 2020 Dec;6(4):54-61
pubmed: 34195461
Biomed Pharmacother. 2018 Dec;108:184-193
pubmed: 30219675
Toxics. 2020 Feb 11;8(1):
pubmed: 32053893
Gastroenterology. 2012 Mar;142(3):543-551.e7
pubmed: 22108198
Science. 2012 Oct 5;338(6103):120-3
pubmed: 22903521
Genome Biol. 2016 Jul 28;17(1):163
pubmed: 27468850
Immunol Rev. 2020 Sep;297(1):207-224
pubmed: 32658330
Pharmacol Res. 2021 Dec;174:105966
pubmed: 34728366
Toxins (Basel). 2021 Jun 11;13(6):
pubmed: 34208170
Microbiol Spectr. 2016 Dec;4(6):
pubmed: 28084212
Cancer Res. 2008 Dec 1;68(23):9909-17
pubmed: 19047172
Science. 2017 Sep 15;357(6356):1156-1160
pubmed: 28912244
Int J Mol Sci. 2019 Apr 25;20(8):
pubmed: 31027304
FASEB J. 2002 Mar;16(3):365-72
pubmed: 11874985
Immunity. 2015 Feb 17;42(2):344-355
pubmed: 25680274
Gut. 2015 Mar;64(3):459-68
pubmed: 24906974
Syst Appl Microbiol. 2002 Dec;25(4):483-90
pubmed: 12583707
Res Microbiol. 2002 Apr;153(3):165-71
pubmed: 12002566
Science. 2013 Nov 22;342(6161):967-70
pubmed: 24264989
Neoplasia. 2022 Oct;32:100829
pubmed: 35933824
Sci Total Environ. 2021 Sep 20;788:147738
pubmed: 34023603