High
ME1
acute myeloid leukemia
biomarker
hematopoietic stem cell transplantation
prognosis
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
31 Dec 2022
31 Dec 2022
Historique:
received:
17
08
2022
revised:
09
12
2022
accepted:
26
12
2022
entrez:
8
1
2023
pubmed:
9
1
2023
medline:
9
1
2023
Statut:
epublish
Résumé
Several laboratory and clinical variables have been reported to be associated with the outcome of intensive chemotherapy for acute myeloid leukemia (AML), but only a few have been tested in the context of hematopoietic stem cell transplant (HSCT). This study aimed to identify genes whose expression of AML at diagnosis were associated with survival after HSCT. For this purpose, three publicly available adult AML cohorts (TCGA, BeatAML, and HOVON), whose patients were treated with intensive chemotherapy and then subjected to allogeneic or autologous HSCT, were included in this study. After whole transcriptome analysis, we identified
Identifiants
pubmed: 36612292
pii: cancers15010296
doi: 10.3390/cancers15010296
pmc: PMC9818450
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Fundação de Amparo à Pesquisa do Estado de São Paulo
ID : 2017/08430-5
Organisme : Fundação de Amparo à Pesquisa do Estado de São Paulo
ID : 2013/08135-2
Organisme : Fundação de Amparo à Pesquisa do Estado de São Paulo
ID : 2017/23117-1
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