Induction of ATF4-Regulated Atrogenes Is Uncoupled from Muscle Atrophy during Disuse in Halofuginone-Treated Mice and in Hibernating Brown Bears.
ATF4
TGF-β/BMP signalling
atrogenes
halofuginone
hibernating bear
hindlimb suspension
muscle atrophy
skeletal muscle
unloading
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
30 Dec 2022
30 Dec 2022
Historique:
received:
14
10
2022
revised:
21
12
2022
accepted:
22
12
2022
entrez:
8
1
2023
pubmed:
9
1
2023
medline:
11
1
2023
Statut:
epublish
Résumé
Activating transcription factor 4 (ATF4) is involved in muscle atrophy through the overexpression of some atrogenes. However, it also controls the transcription of genes involved in muscle homeostasis maintenance. Here, we explored the effect of ATF4 activation by the pharmacological molecule halofuginone during hindlimb suspension (HS)-induced muscle atrophy. Firstly, we reported that periodic activation of ATF4-regulated atrogenes (
Identifiants
pubmed: 36614063
pii: ijms24010621
doi: 10.3390/ijms24010621
pmc: PMC9820832
pii:
doi:
Substances chimiques
Activating Transcription Factor 4
145891-90-3
Transforming Growth Factor beta
0
Atf4 protein, mouse
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Centre National d'Études Spatiales
ID : #865, #974, #1006, #1905
Organisme : Agence Nationale de la Recherche
ID : B-Strong ANR-22-CE14-0018
Organisme : Université Clermont Auvergne
ID : iSITE-Challenge3
Références
Cancer Cell. 2012 Nov 13;22(5):631-44
pubmed: 23153536
Physiol Zool. 1998 Jul-Aug;71(4):414-24
pubmed: 9678502
Am J Physiol Endocrinol Metab. 2013 Oct 1;305(7):E907-15
pubmed: 23941879
Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18117-22
pubmed: 16330774
Oncogene. 2010 Aug 5;29(31):4424-35
pubmed: 20514020
J Biosci. 2020;45:
pubmed: 32457283
Biochim Biophys Acta. 2014 Jul;1843(7):1339-47
pubmed: 24703880
Med Sci Sports Exerc. 2015 Jun;47(6):1301-5
pubmed: 25222820
Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5266-E5275
pubmed: 28607086
J Appl Physiol (1985). 2008 Jan;104(1):170-7
pubmed: 17916675
Exerc Sport Sci Rev. 2013 Apr;41(2):107-15
pubmed: 23089927
Physiol Biochem Zool. 2008 Mar-Apr;81(2):138-47
pubmed: 18173360
Cell Metab. 2009 Dec;10(6):507-15
pubmed: 19945408
Mol Endocrinol. 2010 Apr;24(4):790-9
pubmed: 20197309
Cell Signal. 2014 Jul;26(7):1385-91
pubmed: 24657471
Eur J Appl Physiol. 2004 Dec;93(3):294-305
pubmed: 15338217
Hum Mol Genet. 2018 Aug 15;27(16):2817-2829
pubmed: 29771357
Am J Physiol Cell Physiol. 2009 Jun;296(6):C1248-57
pubmed: 19357234
J Biol Chem. 2019 May 17;294(20):8197-8217
pubmed: 30926605
Exp Gerontol. 2019 Jan;115:19-31
pubmed: 30448397
Biochim Biophys Acta. 2016 Jan;1862(1):1-11
pubmed: 26454207
Int J Mol Sci. 2020 Jul 04;21(13):
pubmed: 32635462
Cold Spring Harb Perspect Biol. 2016 Oct 3;8(10):
pubmed: 27449814
Exp Cell Res. 2010 Apr 1;316(6):1061-9
pubmed: 20060825
Dis Model Mech. 2013 Jan;6(1):25-39
pubmed: 23268536
Nat Genet. 2013 Nov;45(11):1309-18
pubmed: 24076600
J Leukoc Biol. 2017 Dec;102(6):1333-1345
pubmed: 28986385
EMBO Rep. 2016 Oct;17(10):1374-1395
pubmed: 27629041
Free Radic Biol Med. 2016 Sep;98:103-112
pubmed: 27184957
PLoS Biol. 2021 Mar 11;19(3):e3001096
pubmed: 33705388
Mol Cell. 2003 Mar;11(3):619-33
pubmed: 12667446
J Cachexia Sarcopenia Muscle. 2020 Aug;11(4):1104-1120
pubmed: 32096609
Biochimie. 2019 Nov;166:251-269
pubmed: 31325479
J Bone Metab. 2020 Aug;27(3):151-165
pubmed: 32911580
J Nutr. 2022 Apr 1;152(4):926-938
pubmed: 34958390
Wiley Interdiscip Rev Dev Biol. 2013 Jan-Feb;2(1):47-63
pubmed: 23799630
FASEB J. 2007 Jan;21(1):140-55
pubmed: 17116744
Molecules. 2015 Jan 05;20(1):573-94
pubmed: 25569515
Cell Tissue Res. 2007 Apr;328(1):153-66
pubmed: 17180598
Ann Transl Med. 2020 Dec;8(23):1595
pubmed: 33437794
J Am Soc Nephrol. 2006 Jul;17(7):1807-19
pubmed: 16738015
J Cell Biol. 2012 Jun 25;197(7):997-1008
pubmed: 22711699
Theranostics. 2021 Jul 25;11(17):8464-8479
pubmed: 34373753
J Biol Chem. 2015 Oct 16;290(42):25497-511
pubmed: 26338703
Neuromuscul Disord. 2008 Nov;18(11):857-68
pubmed: 18672370
Nat Med. 2013 Jan;19(1):83-92
pubmed: 23202295
Mol Cell Biol. 2017 May 2;37(10):
pubmed: 28242652
Cells. 2021 Jul 23;10(8):
pubmed: 34440643
Am J Physiol Cell Physiol. 2011 Dec;301(6):C1316-24
pubmed: 21900687
Am J Physiol Endocrinol Metab. 2014 Aug 1;307(3):E245-61
pubmed: 24895282
BMC Res Notes. 2012 Sep 20;5:513
pubmed: 22994964
Molecules. 2021 Jan 14;26(2):
pubmed: 33466753
Nat Chem Biol. 2012 Feb 12;8(3):311-7
pubmed: 22327401
Comp Biochem Physiol B Biochem Mol Biol. 2007 May;147(1):20-8
pubmed: 17307375
J Cell Biol. 2013 Oct 28;203(2):345-57
pubmed: 24145169
J Am Med Dir Assoc. 2016 Sep 1;17(9):789-96
pubmed: 27324808
Sci Transl Med. 2012 Jan 25;4(118):118ra11
pubmed: 22277968
J Biol Chem. 2020 Feb 28;295(9):2787-2803
pubmed: 31953319
J Physiol Sci. 2022 Mar 9;72(1):6
pubmed: 35264097
FASEB J. 2016 Sep;30(9):3053-68
pubmed: 27206451
J Biol Chem. 2012 Aug 10;287(33):27290-301
pubmed: 22692209
Nucleic Acids Res. 2013 Sep;41(16):7683-99
pubmed: 23804767
Front Cell Neurosci. 2015 May 18;9:170
pubmed: 26041991
J Clin Biochem Nutr. 2019 Jan;64(1):1-12
pubmed: 30705506
Int J Mol Sci. 2021 May 13;22(10):
pubmed: 34068411
Front Neurol. 2021 Jun 17;12:636719
pubmed: 34220666
Trends Endocrinol Metab. 2014 Sep;25(9):464-71
pubmed: 25042839
FASEB J. 2019 Apr;33(4):5654-5666
pubmed: 30681896
PLoS One. 2009;4(1):e4170
pubmed: 19137072
Am J Physiol Cell Physiol. 2009 Jun;296(6):C1258-70
pubmed: 19357233
Int J Mol Sci. 2021 Jun 30;22(13):
pubmed: 34209117
Sci Transl Med. 2021 Aug 4;13(605):
pubmed: 34349036
Neuromuscul Disord. 2020 Jun;30(6):472-482
pubmed: 32451154
Biotechniques. 1999 Feb;26(2):202-4, 206
pubmed: 10023525