Antioxidant and Anti-Skin Aging Potential of Selected Thai Plants: In Vitro Evaluation and In Silico Target Prediction.

Anacardium occidentale Areca catechu Glochidion zeylanicum Senna alata anti-aging anti-elastase anti-tyrosinase antioxidant phytomedicine proanthocyanidin

Journal

Plants (Basel, Switzerland)
ISSN: 2223-7747
Titre abrégé: Plants (Basel)
Pays: Switzerland
ID NLM: 101596181

Informations de publication

Date de publication:
22 Dec 2022
Historique:
received: 31 10 2022
revised: 17 12 2022
accepted: 19 12 2022
entrez: 8 1 2023
pubmed: 9 1 2023
medline: 9 1 2023
Statut: epublish

Résumé

The skin is the largest organ that performs a variety of the body's essential functions. Impairment of skin structure and functions during the aging process might severely impact our health and well-being. Extensive evidence suggests that reactive oxygen species play a fundamental role in skin aging through the activation of the related degradative enzymes. Here, the 16 Thai medicinal plant species were screened for their potential anti-skin aging properties. All extracts were investigated for total phenolic and flavonoid contents, antioxidant, anti-elastase, and anti-tyrosinase activities, as well as the binding ability of compounds with target enzymes by molecular docking. Among all the plants screened, the leaves of

Identifiants

pubmed: 36616194
pii: plants12010065
doi: 10.3390/plants12010065
pmc: PMC9823845
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : The Thailand Science research and Innovation Fund Chulalongkorn University
ID : CU_FRB65_hea (91)_198_53_01
Organisme : The Office of the Permanent Secretary, Ministry of Higher Education, Science, Research and In-novation
ID : RGNS 63-003

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Auteurs

Kamonwan Chaikhong (K)

Graduate Program in Clinical Biochemistry and Molecular Medicine, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.

Sawarin Chumpolphant (S)

Graduate Program in Clinical Biochemistry and Molecular Medicine, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.

Panthakarn Rangsinth (P)

Department of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.

Chanin Sillapachaiyaporn (C)

Graduate Program in Clinical Biochemistry and Molecular Medicine, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.

Siriporn Chuchawankul (S)

Department of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.

Tewin Tencomnao (T)

Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Natural Products for Neuroprotection and Anti-Ageing Research Unit, Chulalongkorn University, Bangkok 10330, Thailand.

Anchalee Prasansuklab (A)

Natural Products for Neuroprotection and Anti-Ageing Research Unit, Chulalongkorn University, Bangkok 10330, Thailand.
College of Public Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.

Classifications MeSH