Genetic, epigenetic and enviromental influencing factors on the regulation of precocious and delayed puberty.
delayed puberty
endocrine disruptors
enviromental factors
epigenetic
genetic
precocious puberty
Journal
Frontiers in endocrinology
ISSN: 1664-2392
Titre abrégé: Front Endocrinol (Lausanne)
Pays: Switzerland
ID NLM: 101555782
Informations de publication
Date de publication:
2022
2022
Historique:
received:
15
08
2022
accepted:
08
12
2022
entrez:
9
1
2023
pubmed:
10
1
2023
medline:
11
1
2023
Statut:
epublish
Résumé
The pubertal development onset is controlled by a network of genes that regulate the gonadotropin releasing hormone (GnRH) pulsatile release and the subsequent increase of the circulating levels of pituitary gonadotropins that activate the gonadal function. Although the transition from pre-pubertal condition to puberty occurs physiologically in a delimited age-range, the inception of pubertal development can be anticipated or delayed due to genetic and epigenetic changes or environmental conditions. Most of the genetic and epigenetic alterations concern genes which encode for kisspeptin, GnRH, LH, FSH and their receptor, which represent crucial factors of the hypothalamic-pituitary-gonadal (HPG) axis. Recent data indicate a central role of the epigenome in the regulation of genes in the hypothalamus and pituitary that could mediate the flexibility of pubertal timing. Identification of epigenetically regulated genes, such as Makorin ring finger 3 (
Identifiants
pubmed: 36619551
doi: 10.3389/fendo.2022.1019468
pmc: PMC9813382
doi:
Substances chimiques
Gonadotropin-Releasing Hormone
33515-09-2
MKRN3 protein, human
EC 2.3.2.27
Ubiquitin-Protein Ligases
EC 2.3.2.27
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1019468Informations de copyright
Copyright © 2022 Faienza, Urbano, Moscogiuri, Chiarito, De Santis and Giordano.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Clin Endocrinol Metab. 2016 Jun;101(6):2588-93
pubmed: 27057785
Nutrients. 2021 Jan 28;13(2):
pubmed: 33525559
N Engl J Med. 2012 Feb 2;366(5):443-53
pubmed: 22296078
J Clin Endocrinol Metab. 2010 May;95(5):2276-80
pubmed: 20237166
Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11524-9
pubmed: 21700882
Chemosphere. 2008 Oct;73(6):999-1004
pubmed: 18707752
J Neurosci. 2018 Feb 28;38(9):2283-2293
pubmed: 29374136
Clin Epigenetics. 2018 Nov 22;10(1):146
pubmed: 30466473
Front Neuroendocrinol. 2015 Jul;38:12-36
pubmed: 25592640
Mol Endocrinol. 2006 Nov;20(11):2898-908
pubmed: 16840533
N Engl J Med. 2013 Jun 27;368(26):2467-75
pubmed: 23738509
Int J Dev Neurosci. 2013 Oct;31(6):452-62
pubmed: 23510953
Lancet Diabetes Endocrinol. 2016 Mar;4(3):254-264
pubmed: 26852256
Arch Toxicol. 2018 Aug;92(8):2629-2643
pubmed: 29947892
C R Biol. 2017 Sep - Oct;340(9-10):432-438
pubmed: 28826787
Front Endocrinol (Lausanne). 2019 Dec 06;10:828
pubmed: 31920956
Epigenetics. 2020 Jan - Feb;15(1-2):183-198
pubmed: 31282290
Signal Transduct Target Ther. 2022 Mar 24;7(1):95
pubmed: 35332121
Biochim Biophys Acta. 2003 Feb 17;1619(3):263-8
pubmed: 12573486
J Clin Endocrinol Metab. 2019 Aug 1;104(8):3049-3067
pubmed: 31042289
Endocrinology. 2013 May;154(5):1873-84
pubmed: 23525218
Gynecol Endocrinol. 2019 Aug;35(8):732-736
pubmed: 30806524
Biochem Biophys Res Commun. 2018 Jun 22;501(2):478-485
pubmed: 29746863
Nature. 2014 Oct 02;514(7520):92-97
pubmed: 25231870
Front Neurosci. 2014 Nov 28;8:387
pubmed: 25506316
Arch Environ Contam Toxicol. 2015 Jan;68(1):38-45
pubmed: 25213476
Endocrinology. 1993 Nov;133(5):2399-402
pubmed: 8104781
Endocrinology. 2011 Apr;152(4):1616-26
pubmed: 21285314
Eur J Endocrinol. 2021 May 04;184(6):733-749
pubmed: 33769962
Nat Rev Endocrinol. 2021 Feb;17(2):83-96
pubmed: 33288917
Nat Neurosci. 2021 Dec;24(12):1660-1672
pubmed: 34795451
Hum Mol Genet. 2019 Apr 15;28(8):1357-1368
pubmed: 30608578
Environ Health Perspect. 2018 Sep;126(9):97004
pubmed: 30203993
Science. 2022 Sep 2;377(6610):eabq4515
pubmed: 36048943
Nature. 2013 Oct 24;502(7472):472-9
pubmed: 24153300
Environ Int. 2014 Apr;65:107-15
pubmed: 24486968
J Clin Invest. 2017 Mar 1;127(3):1061-1074
pubmed: 28218624
Front Endocrinol (Lausanne). 2020 May 19;11:253
pubmed: 32508745
Mol Cell Endocrinol. 2016 Oct 15;434:250-65
pubmed: 27402603
Front Endocrinol (Lausanne). 2019 Jun 26;10:423
pubmed: 31293522
Horm Res Paediatr. 2013;80(2):69-77
pubmed: 23899516
J Biol Chem. 2017 Dec 15;292(50):20720-20731
pubmed: 29054929
Endocrinology. 2018 Jan 1;159(1):132-144
pubmed: 29165653
Toxicology. 2013 Dec 6;314(1):65-75
pubmed: 24056307
Pediatrics. 2010 Sep;126(3):e591-600
pubmed: 20696722
J Clin Endocrinol Metab. 2017 May 1;102(5):1557-1567
pubmed: 28324015
Nat Neurosci. 2016 Jun;19(6):835-44
pubmed: 27135215
J Clin Endocrinol Metab. 2018 Feb 1;103(2):649-659
pubmed: 29161441
J Endocrinol Invest. 2017 Aug;40(8):789-802
pubmed: 28251550
Int J Hyg Environ Health. 2021 Jan;231:113633
pubmed: 33045491
Nat Genet. 2009 Mar;41(3):354-358
pubmed: 19079066
Mol Cell Endocrinol. 2021 Jul 15;532:111302
pubmed: 33964320
Front Neuroendocrinol. 2011 Jan;32(1):95-107
pubmed: 21129392
EMBO J. 2020 Oct 1;39(19):e104633
pubmed: 32761635
J Clin Endocrinol Metab. 2014 Mar;99(3):861-70
pubmed: 24423288
J Endocr Soc. 2019 Mar 25;3(5):979-995
pubmed: 31041429
J Clin Endocrinol Metab. 2015 May;100(5):1920-6
pubmed: 25695892
Natl Sci Rev. 2020 Mar;7(3):671-685
pubmed: 34692086
Int J Environ Res Public Health. 2017 Oct 24;14(10):
pubmed: 29064384
Int J Androl. 2010 Apr;33(2):346-59
pubmed: 20487042
Mol Cell Endocrinol. 2010 Aug 5;324(1-2):39-44
pubmed: 20298746
J Neuroendocrinol. 2020 Feb;32(2):e12823
pubmed: 31872920
Endocrinology. 2002 Jul;143(7):2767-74
pubmed: 12072412
N Engl J Med. 2011 Jan 20;364(3):215-25
pubmed: 21247312
J Clin Endocrinol Metab. 2014 Jun;99(6):E1097-103
pubmed: 24628548
Front Horm Res. 2010;39:37-50
pubmed: 20389084
PLoS One. 2019 Jul 30;14(7):e0220530
pubmed: 31361780
Sci Transl Med. 2022 Oct 5;14(665):eabh2369
pubmed: 36197968
N Engl J Med. 2008 Feb 14;358(7):709-15
pubmed: 18272894
Front Horm Res. 2010;39:133-141
pubmed: 20389091
Front Neuroendocrinol. 2015 Jan;36:90-107
pubmed: 25171849
Endocr Relat Cancer. 2021 Oct 15;28(12):R271-R287
pubmed: 34627131
J Neurosci. 2012 Jan 18;32(3):932-45
pubmed: 22262891
Horm Res Paediatr. 2012;78(3):144-50
pubmed: 22964795
J Clin Endocrinol Metab. 2019 Jun 1;104(6):2112-2120
pubmed: 30462238
Nat Genet. 2010 Jul;42(7):626-30
pubmed: 20512147
Endocr Connect. 2020 May;9(5):R124-R133
pubmed: 32348961
Nat Rev Endocrinol. 2020 Sep;16(9):519-533
pubmed: 32620937
Nat Genet. 2009 Jun;41(6):729-33
pubmed: 19448623
Endocr Connect. 2020 Aug;9(8):845-857
pubmed: 32755991
J Mol Endocrinol. 2015 Jun;54(3):R131-9
pubmed: 25957321
EMBO Mol Med. 2016 Jun 01;8(6):626-42
pubmed: 27137492
Proc Natl Acad Sci U S A. 2012 May 15;109(20):E1294-301
pubmed: 22505735
Hum Reprod. 2001 May;16(5):1020-6
pubmed: 11331654
Sci Rep. 2016 Jun 28;6:28657
pubmed: 27349168
Mol Cells. 2011 Aug;32(2):161-5
pubmed: 21643850
Proc Natl Acad Sci U S A. 1993 Nov 1;90(21):10130-4
pubmed: 7694282
Semin Reprod Med. 2019 Jul;37(4):174-181
pubmed: 31972862
Reprod Toxicol. 2012 Apr;33(2):198-204
pubmed: 21549831
Nat Rev Mol Cell Biol. 2010 Sep;11(9):607-20
pubmed: 20683471
Hum Reprod. 2016 Jun;31(6):1363-74
pubmed: 27094476
J Clin Endocrinol Metab. 2015 Apr;100(4):E646-54
pubmed: 25636053
J Med Genet. 2014 Aug;51(8):495-501
pubmed: 24891339
Endocrinology. 1999 Nov;140(11):5257-66
pubmed: 10537156
Nat Neurosci. 2013 Mar;16(3):281-9
pubmed: 23354331
Best Pract Res Clin Endocrinol Metab. 2019 Jun;33(3):101265
pubmed: 31000487
Paediatr Perinat Epidemiol. 2019 Jan;33(1):70-78
pubmed: 30307620
Nature. 2014 Mar 20;507(7492):371-5
pubmed: 24646999
J Neuroendocrinol. 2018 Jul;30(7):e12589
pubmed: 29520866
Front Endocrinol (Lausanne). 2019 May 21;10:312
pubmed: 31164866
Endocrine. 2018 Jan;59(1):203-208
pubmed: 28299573
Front Genet. 2019 Mar 19;10:228
pubmed: 30941164
Popul Res Policy Rev. 2017 Oct;36(5):717-738
pubmed: 30127541
Nucleic Acids Res. 2021 Apr 19;49(7):3796-3813
pubmed: 33744966
Best Pract Res Clin Endocrinol Metab. 2019 Jun;33(3):101300
pubmed: 31401055
Neuroendocrinology. 2019;108(3):172-189
pubmed: 30537700
Endocrinology. 2016 Sep;157(9):3588-603
pubmed: 27384303
FASEB J. 2014 Jul;28(7):3124-33
pubmed: 24744145
Sci Total Environ. 2016 Sep 1;563-564:1086-7
pubmed: 27216966
J Assist Reprod Genet. 2017 May;34(5):549-562
pubmed: 28281142