Hypothesis: Viral infections of pregnant women may be early triggers of childhood type 1 diabetes and other autoimmune disease.
Atopic dermatitis
Autoimmune disease
Childhood
Multiple sclerosis
Thyroiditis
Type 1 diabetes
Viruses
Journal
Journal of autoimmunity
ISSN: 1095-9157
Titre abrégé: J Autoimmun
Pays: England
ID NLM: 8812164
Informations de publication
Date de publication:
02 2023
02 2023
Historique:
received:
08
09
2022
revised:
06
12
2022
accepted:
06
12
2022
pubmed:
10
1
2023
medline:
3
3
2023
entrez:
9
1
2023
Statut:
ppublish
Résumé
Children and adolescents with early onset autoimmune diseases have a different seasonality of month of birth than the general population. This pattern is consistent with an infection during pregnancy affecting the fetus or an infection immediately after birth that act as early triggers of the autoimmune diseases. We present data supporting the use of Rotavirus vaccinations in the reduction of incidence of childhood T1D and propose further investigations into whether other anti-virus vaccinations may reduce the burden of other autoimmune diseases such as multiple sclerosis, atopic dermatitis, psoriasis and subtypes of rheumatoid arthritis, Hashimoto thyroiditis.
Identifiants
pubmed: 36621175
pii: S0896-8411(22)00185-8
doi: 10.1016/j.jaut.2022.102977
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
102977Informations de copyright
Copyright © 2022 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest None of the authors has anything to declare.