Brain Stress Test for Assessing Risk for Hemodynamic Stroke.
Brain stress test
CO2
Cerebrovascular reserve
Hypercapnia
MRI
Stroke
Journal
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
ISSN: 0317-1671
Titre abrégé: Can J Neurol Sci
Pays: England
ID NLM: 0415227
Informations de publication
Date de publication:
10 Jan 2023
10 Jan 2023
Historique:
pubmed:
11
1
2023
medline:
11
1
2023
entrez:
10
1
2023
Statut:
aheadofprint
Résumé
In patients with intracranial steno-occlusive disease (SOD), the risk of hemodynamic stroke depends on the poststenotic vasodilatory reserve. Cerebrovascular reactivity (CVR) is a test for vasodilatory reserve. We tested for vasodilatory reserve by using P In this retrospective study, 100 consecutive patients with symptomatic intracranial SOD that had undergone CVR testing were identified. CVR was measured as % BOLD MR signal intensity/mmHg P 83 patients were included in the study. CVR was normal in 14 patients and impaired in 69 patients ipsilateral to the lesion. Of these, 53 underwent surgical revascularization. CVR and symptoms improved in 86% of the latter. The overall incidence of stroke was 4.8 % (4/83). All strokes occurred in patients with impaired CVR (4/69; 2/53 in the surgical group, all in the nonrevascularized hemisphere), and none in patients with normal CVR (0/14). Our study confirms that CO
Sections du résumé
BACKGROUND
BACKGROUND
In patients with intracranial steno-occlusive disease (SOD), the risk of hemodynamic stroke depends on the poststenotic vasodilatory reserve. Cerebrovascular reactivity (CVR) is a test for vasodilatory reserve. We tested for vasodilatory reserve by using P
METHODS
METHODS
In this retrospective study, 100 consecutive patients with symptomatic intracranial SOD that had undergone CVR testing were identified. CVR was measured as % BOLD MR signal intensity/mmHg P
RESULTS
RESULTS
83 patients were included in the study. CVR was normal in 14 patients and impaired in 69 patients ipsilateral to the lesion. Of these, 53 underwent surgical revascularization. CVR and symptoms improved in 86% of the latter. The overall incidence of stroke was 4.8 % (4/83). All strokes occurred in patients with impaired CVR (4/69; 2/53 in the surgical group, all in the nonrevascularized hemisphere), and none in patients with normal CVR (0/14).
CONCLUSION
CONCLUSIONS
Our study confirms that CO
Identifiants
pubmed: 36624923
pii: S0317167123000033
doi: 10.1017/cjn.2023.3
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM