The role of immunotherapy and targeted therapy in the multimodal therapy for resectable lung cancer.


Journal

Journal of surgical oncology
ISSN: 1096-9098
Titre abrégé: J Surg Oncol
Pays: United States
ID NLM: 0222643

Informations de publication

Date de publication:
Feb 2023
Historique:
revised: 14 11 2022
received: 07 11 2022
accepted: 18 11 2022
entrez: 11 1 2023
pubmed: 12 1 2023
medline: 14 1 2023
Statut: ppublish

Résumé

As the immunotherapeutic milieu in resectable nonsmall cell lung cancer continues to evolve, the field of thoracic oncology actively moves towards better patient selection based on biomarkers and oncogenic drivers. In this article, we review the current standard of oncologic care in this population and discuss the ongoing phase III clinical trials investigating the use of immunotherapy or targeted therapy in the perioperative period. We also discuss genotyping initiatives, biomarkers, and trial endpoints.

Identifiants

pubmed: 36630093
doi: 10.1002/jso.27166
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

275-281

Subventions

Organisme : Mason Family Philanthropic Research Fund

Informations de copyright

© 2022 Wiley Periodicals LLC.

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Auteurs

Nathaniel Deboever (N)

Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Michael Eisenberg (M)

Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Alexis Chidi (A)

Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Boris Sepesi (B)

Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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