Integrated therapy of intraductal irrigations and sialoendoscopies of salivary glands to improve mouth dryness.

dry mouth intraductal irrigation salivary flow salivary gland dysfunction salivary glands sialo-centesis sialoendoscopy

Journal

Oral diseases
ISSN: 1601-0825
Titre abrégé: Oral Dis
Pays: Denmark
ID NLM: 9508565

Informations de publication

Date de publication:
11 Jan 2023
Historique:
revised: 22 10 2022
received: 23 08 2021
accepted: 20 12 2022
pubmed: 12 1 2023
medline: 12 1 2023
entrez: 11 1 2023
Statut: aheadofprint

Résumé

To assess the combination of salivary gland intraductal irrigations (IG) followed by sialoendoscopy irrigations (SI) of the parotid gland on the improvement of salivary gland secretory dysfunction (SGSD). We retrospectively analyzed the records of SGSD patients who underwent major salivary gland IG followed by SI during 2014-2020. Records included demographics, systemic background, signs, and symptoms. Improvement was assessed by comparing the mean unstimulated and stimulated whole salivary flow rate (UWSF, SWSF) from the baseline point (before IG procedure) to the last point (after SI) using repeated measures. The between-subjects effects of various factors and covariants were analyzed using repeated measures ANCOVA. One hundred patients were included with an age range of 15-83 years (mean age of 60.1 ± 13.1 years). Improvement was detected on UWSF measurements (p = 0.031, F = 3.83), but not on SWSF measurements (p = 0.165, F = 1.85). The between-subjects effects on UWSF measurements were statistically significant for sex (p = 0.003, F = 9.526) and salivary gland manipulators use (p < 0.001, F = 15.107) and for the interaction between sex and salivary gland manipulators use (p- = 0.002, F = 9.709). Results of long-term follow-up for 10.87 ± 11.79 months after the SI procedure demonstrated sustained improvement in UWSF measurements (p = 0.011, F = 4.91). The combination of IG followed by SI increases UWSF salivary secretion in SGSD patients for a relatively extended duration.

Identifiants

pubmed: 36630587
doi: 10.1111/odi.14501
doi:

Types de publication

Journal Article

Langues

eng

Informations de copyright

© 2023 The Authors. Oral Diseases published by Wiley Periodicals LLC.

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Auteurs

Doron J Aframian (DJ)

Sjögren's syndrome Center, Hadassah Medical Center, Jerusalem, Israel.
Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Department of Oral Medicine, Sedation & Maxillofacial Imaging, Hadassah Medical Center, Jerusalem, Israel.

Ori Bar (O)

Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

Asaf Wilensky (A)

Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Department of Periodontology, Hadassah Medical Center, Jerusalem, Israel.

Chen Nadler (C)

Sjögren's syndrome Center, Hadassah Medical Center, Jerusalem, Israel.
Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Department of Oral Medicine, Sedation & Maxillofacial Imaging, Hadassah Medical Center, Jerusalem, Israel.

Galit Almoznino (G)

Sjögren's syndrome Center, Hadassah Medical Center, Jerusalem, Israel.
Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Department of Oral Medicine, Sedation & Maxillofacial Imaging, Hadassah Medical Center, Jerusalem, Israel.
Big Biomedical Data Research Laboratory, Dean's office, Hadassah Medical Center, Jerusalem, Israel.

Classifications MeSH