Brief structured respiration practices enhance mood and reduce physiological arousal.

anxiety autonomic breathwork heart rate variability limbic mindfulness meditation mood physiology sleep stress wearable

Journal

Cell reports. Medicine
ISSN: 2666-3791
Titre abrégé: Cell Rep Med
Pays: United States
ID NLM: 101766894

Informations de publication

Date de publication:
17 01 2023
Historique:
received: 02 04 2022
revised: 06 09 2022
accepted: 15 12 2022
pubmed: 12 1 2023
medline: 21 1 2023
entrez: 11 1 2023
Statut: ppublish

Résumé

Controlled breathwork practices have emerged as potential tools for stress management and well-being. Here, we report a remote, randomized, controlled study (NCT05304000) of three different daily 5-min breathwork exercises compared with an equivalent period of mindfulness meditation over 1 month. The breathing conditions are (1) cyclic sighing, which emphasizes prolonged exhalations; (2) box breathing, which is equal duration of inhalations, breath retentions, and exhalations; and (3) cyclic hyperventilation with retention, with longer inhalations and shorter exhalations. The primary endpoints are improvement in mood and anxiety as well as reduced physiological arousal (respiratory rate, heart rate, and heart rate variability). Using a mixed-effects model, we show that breathwork, especially the exhale-focused cyclic sighing, produces greater improvement in mood (p < 0.05) and reduction in respiratory rate (p < 0.05) compared with mindfulness meditation. Daily 5-min cyclic sighing has promise as an effective stress management exercise.

Identifiants

pubmed: 36630953
pii: S2666-3791(22)00474-8
doi: 10.1016/j.xcrm.2022.100895
pmc: PMC9873947
pii:
doi:

Types de publication

Randomized Controlled Trial Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

100895

Subventions

Organisme : NEI NIH HHS
ID : P30 EY026877
Pays : United States

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests A.D.H. became an advisor to WHOOP in June of 2022.

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Auteurs

Melis Yilmaz Balban (MY)

Department of Neurobiology, School of Medicine, Stanford University, Stanford, CA 94305, USA.

Eric Neri (E)

Department of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA 94305, USA.

Manuela M Kogon (MM)

Department of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA 94305, USA; Stanford Center for Integrative Medicine, Stanford Health Care, Palo Alto, CA 94304, USA.

Lara Weed (L)

Department of Bioengineering, School of Engineering and School of Medicine, Stanford University, Stanford, CA 94305, USA.

Bita Nouriani (B)

Department of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA 94305, USA.

Booil Jo (B)

Department of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA 94305, USA.

Gary Holl (G)

Department of Neurobiology, School of Medicine, Stanford University, Stanford, CA 94305, USA.

Jamie M Zeitzer (JM)

Department of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA 94305, USA; Mental Illness Research Education and Clinical Center, VA Palo Alto Health Care Service, Palo Alto, CA 94304, USA.

David Spiegel (D)

Department of Psychiatry & Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA 94305, USA; Center for Stress and Health, School of Medicine, Stanford University, Stanford, CA 94305, USA. Electronic address: dspiegel@stanford.edu.

Andrew D Huberman (AD)

Department of Neurobiology, School of Medicine, Stanford University, Stanford, CA 94305, USA; Department of Ophthalmology, School of Medicine, Stanford University, Stanford, CA 94305, USA; BioX, School of Medicine, Stanford University, Stanford, CA 94305, USA. Electronic address: adh1@stanford.edu.

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Classifications MeSH