Attention-deficit hyperactivity disorder is associated with relatively short stature among adolescents.


Journal

Acta paediatrica (Oslo, Norway : 1992)
ISSN: 1651-2227
Titre abrégé: Acta Paediatr
Pays: Norway
ID NLM: 9205968

Informations de publication

Date de publication:
04 2023
Historique:
revised: 21 12 2022
received: 23 08 2022
accepted: 10 01 2023
pubmed: 13 1 2023
medline: 15 3 2023
entrez: 12 1 2023
Statut: ppublish

Résumé

To estimate the association between attention-deficit hyperactivity disorder (ADHD) and relatively short stature (RSS) among adolescents. Participants in the Israeli Youth Health and Nutrition Survey (2015-2016), a cross-sectional school-based study, completed self-administered questionnaires and underwent anthropometric measurements. Height z-score < -0.7 (<25th percentile) was defined as RSS. Multivariable logistic regression analyses assessed the relation between ADHD and RSS, controlling for age, sex, body mass index (BMI) and socioeconomic status (Basic Model), and also for lifestyle factors such as physical activity, sleep duration, dietary patterns and intakes. Of 4173 participants (11-18 years, 50.2% males), 654 self-reported ever being diagnosed with ADHD; 3519 participants were controls. Overweight (BMI z-score ≥1) and pubertal status were not different among groups. According to the Basic Model, ADHD was significantly associated with RSS (OR 1.25, 95% CI 1.03-1.50), and even after adjustments for lifestyle factors and dietary intake (OR 1.28, 95% CI 1.03-1.58). Stimulant-treated ADHD adolescents had similar height z-scores and lifestyles as those not treated with stimulants. Attention-deficit hyperactivity disorder was associated with RSS. Height deficit may be intrinsic to ADHD or its pharmacotherapy, rather than a consequence of lifestyle alone. Further studies are needed to determine the causal relationship between ADHD and short stature.

Identifiants

pubmed: 36635216
doi: 10.1111/apa.16668
doi:

Substances chimiques

Central Nervous System Stimulants 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

779-786

Informations de copyright

© 2023 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica.

Références

Cabral MDI, Liu S, Soares N. Attention-deficit/hyperactivity disorder: diagnostic criteria, epidemiology, risk factors and evaluation in youth. Transl Pediatr. 2020;9(Suppl 1):S104-s113. doi:10.21037/tp.2019.09.08
de Onis M, Branca F. Childhood stunting: a global perspective. Matern Child Nutr. 2016;12(Suppl 1):12-26. doi:10.1111/mcn.12231
Carucci S, Balia C, Gagliano A, et al. Long term methylphenidate exposure and growth in children and adolescents with ADHD. A systematic review and meta-analysis. Neurosci Biobehav Rev. 2021;120:509-525. doi:10.1016/j.neubiorev.2020.09.031
Cortese S, Moreira-Maia CR, St Fleur D, Morcillo-Peñalver C, Rohde LA, Faraone SV. Association between ADHD and obesity: a systematic review and meta-analysis. Am J Psychiatry. 2016;173(1):34-43. doi:10.1176/appi.ajp.2015.15020266
Ptacek R, Kuzelova H, Paclt I, Zukov I, Fischer S. ADHD and growth: anthropometric changes in medicated and non-medicated ADHD boys. Med Sci Monit. 2009;15(12):Cr595-Cr599.
Yackobovitch-Gavan M, Mimouni-Bloch A, Gabbay U, et al. Sex-specific long-term height and body mass index trajectories of children diagnosed with attention-deficit/hyperactivity disorder and treated with stimulants. J Pediatr. 2021;238:296-304.e4. doi:10.1016/j.jpeds.2021.07.018
Pinhas-Hamiel O, Bardugo A, Reichman B. Attention-deficit hyperactivity disorder and obesity - a National Study of 1.1 million Israeli adolescents. J Clin Endocrinol Metab. 2022;107(4):e1434-e1443. doi:10.1210/clinem/dgab846
Jelenkovic A, Ortega-Alonso A, Rose RJ, Kaprio J, Rebato E, Silventoinen K. Genetic and environmental influences on growth from late childhood to adulthood: a longitudinal study of two Finnish twin cohorts. Am J Hum Biol. 2011;23(6):764-773. doi:10.1002/ajhb.21208
Davallow Ghajar L, DeBoer MD. Children with attention-deficit/hyperactivity disorder are at increased risk for slowed growth and short stature in early childhood. Clin Pediatr (Phila). 2020;59(4-5):401-410. doi:10.1177/0009922820902437
Tandon PS, Sasser T, Gonzalez ES, Whitlock KB, Christakis DA, Stein MA. Physical activity, screen time, and sleep in children with ADHD. J Phys Act Health. 2019;16(6):416-422. doi:10.1123/jpah.2018-0215
Del-Ponte B, Quinte GC, Cruz S, Grellert M, Santos IS. Dietary patterns and attention deficit/hyperactivity disorder (ADHD): a systematic review and meta-analysis. J Affect Disord. 2019;252:160-173. doi:10.1016/j.jad.2019.04.061
Israel Center for Disease Control, Israel Ministry of Health. Mabat youth second national health and nutrition survey of 7th -12th grade students 2015-2016. https://www.health.gov.il/PublicationsFiles/mabat_kids2_11_2015-2016-ENG.pdf
Dor C, Stark AH, Dichtiar R, Keinan-Boker L, Shimony T, Sinai T. Milk and dairy consumption is positively associated with height in adolescents: results from the Israeli National Youth Health and nutrition survey. Eur J Nutr. 2022;61(1):429-438. doi:10.1007/s00394-021-02661-6
Piercy KL, Troiano RP, Ballard RM, et al. The physical activity guidelines for Americans. JAMA. 2018;320(19):2020-2028. doi:10.1001/jama.2018.14854
Paruthi S, Brooks LJ, D'Ambrosio C, et al. Recommended amount of sleep for pediatric populations: a consensus Statement of the American Academy of sleep medicine. J Clin Sleep Med. 2016;12(6):785-786. doi:10.5664/jcsm.5866
Sinai T, Axelrod R. Dietary patterns among adolescents are associated with growth, socioeconomic features, and health-related behaviors. Foods. 2021;10(12):3054. doi:10.3390/foods10123054
Shai I, Rosner BA, Shahar DR, et al. Dietary evaluation and attenuation of relative risk: multiple comparisons between blood and urinary biomarkers, food frequency, and 24-hour recall questionnaires: the DEARR study. J Nutr. 2005;135(3):573-579. doi:10.1093/jn/135.3.573
World Health Organization. Child growth standards. Accessed at https://www.who.int/tools/child-growth-standards
Hwang JW, Seo JY. Parents' perception about child's height and psychopathology in community children with relatively short stature. Ann Pediatr Endocrinol Metab. 2015;20(2):79-85. doi:10.6065/apem.2015.20.2.79
Trumbo P, Schlicker S, Yates AA, Poos M. Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein and amino acids. J Am Diet Assoc. 2002;102(11):1621-1630. doi:10.1016/s0002-8223(02)90346-9
Rowland AS, Skipper BJ, Umbach DM, et al. The prevalence of ADHD in a population-based sample. J Atten Disord. 2015;19(9):741-754. doi:10.1177/1087054713513799
Russell AE, Ford T, Williams R, Russell G. The association between socioeconomic disadvantage and attention deficit/hyperactivity disorder (ADHD): a systematic review. Child Psychiatry Hum Dev. 2016;47(3):440-458. doi:10.1007/s10578-015-0578-3
Mercurio LY, Amanullah S, Gill N, Gjelsvik A. Children with ADHD engage in less physical activity. J Atten Disord. 2021;25(8):1187-1195. doi:10.1177/1087054719887789
Camara B, Padoin C, Bolea B. Relationship between sex hormones, reproductive stages and ADHD: a systematic review. Arch Womens Ment Health. 2022;25(1):1-8. doi:10.1007/s00737-021-01181-w
Pinto AC, Finamor FE Jr, Lengyel AM. Acute dexamethasone administration enhances GH responsiveness to GH releasing peptide-6 (GHRP-6) in man. Clin Endocrinol (Oxf). 1999;51(4):409-414. doi:10.1046/j.1365-2265.1999.00792.x
Pervanidou P, Kolaitis G, Charitaki S, et al. The natural history of neuroendocrine changes in pediatric posttraumatic stress disorder (PTSD) after motor vehicle accidents: progressive divergence of noradrenaline and cortisol concentrations over time. Biol Psychiatry. 2007;62(10):1095-1102. doi:10.1016/j.biopsych.2007.02.008
De Zegher F, Van Den Berghe G, Devlieger H, Eggermont E, Veldhuis JD. Dopamine inhibits growth hormone and prolactin secretion in the human newborn. Pediatr Res. 1993;34(5):642-645. doi:10.1203/00006450-199311000-00016
Howard JT, Walick KS, Rivera JC. Preliminary evidence of an association between ADHD medications and diminished bone health in children and adolescents. J Pediatr Orthop. 2017;37(5):348-354. doi:10.1097/bpo.0000000000000651
Kidwell KM, Van Dyk TR, Lundahl A, Nelson TD. Stimulant medications and sleep for youth with ADHD: a meta-analysis. Pediatrics. 2015;136(6):1144-1153. doi:10.1542/peds.2015-1708
Altszuler AR, Morrow AS, Merrill BM. The effects of stimulant medication and training on sports competence among children with ADHD. J Clin Child Adolesc Psychol. 2019;48(sup1):S155-s167. doi:10.1080/15374416.2016.1270829

Auteurs

Chen Namimi-Halevi (C)

Israel Centre for Disease Control, Israel Ministry of Health, Ramat Gan, Israel.

Chen Dor (C)

Israel Centre for Disease Control, Israel Ministry of Health, Ramat Gan, Israel.

Rita Dichtiar (R)

Israel Centre for Disease Control, Israel Ministry of Health, Ramat Gan, Israel.

Michal Bromberg (M)

Israel Centre for Disease Control, Israel Ministry of Health, Ramat Gan, Israel.
Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Tali Sinai (T)

Israel Centre for Disease Control, Israel Ministry of Health, Ramat Gan, Israel.
School of Nutritional Sciences, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH