Clinical response to EPA supplementation in patients with major depressive disorder is associated with higher plasma concentrations of pro-resolving lipid mediators.


Journal

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
ISSN: 1740-634X
Titre abrégé: Neuropsychopharmacology
Pays: England
ID NLM: 8904907

Informations de publication

Date de publication:
05 2023
Historique:
received: 31 08 2022
accepted: 26 12 2022
revised: 21 12 2022
medline: 5 5 2023
pubmed: 13 1 2023
entrez: 12 1 2023
Statut: ppublish

Résumé

Chronic inflammation has been implicated in the pathophysiology of major depressive disorder (MDD). Activating the resolution of inflammation through ω-3 fatty acid supplementation may prove to be a successful therapeutic strategy for the treatment of MDD. Patients with MDD, body mass index >25 kg/m

Identifiants

pubmed: 36635595
doi: 10.1038/s41386-022-01527-7
pii: 10.1038/s41386-022-01527-7
pmc: PMC10156711
doi:

Substances chimiques

Eicosapentaenoic Acid AAN7QOV9EA
Docosahexaenoic Acids 25167-62-8
Fatty Acids, Omega-3 0
C-Reactive Protein 9007-41-4

Types de publication

Randomized Controlled Trial Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

929-935

Subventions

Organisme : NCCIH NIH HHS
ID : UG3 AT008857
Pays : United States

Informations de copyright

© 2023. The Author(s).

Références

FASEB J. 2019 Jun;33(6):7072-7083
pubmed: 30840838
J Lipid Res. 2013 Sep;54(9):2410-22
pubmed: 23836105
Psychol Med. 1996 May;26(3):477-86
pubmed: 8733206
J Clin Psychiatry. 2014 Dec;75(12):e1428-32
pubmed: 25551239
Mol Aspects Med. 2017 Dec;58:83-92
pubmed: 28341541
Eur Neuropsychopharmacol. 2009 Jan;19(1):34-40
pubmed: 18823760
Nat Immunol. 2005 Dec;6(12):1191-7
pubmed: 16369558
Anal Chem. 2012 Feb 7;84(3):1483-90
pubmed: 22224852
Sci Transl Med. 2016 Aug 24;8(353):353ra111
pubmed: 27559094
J Clin Invest. 2018 Jul 2;128(7):2657-2669
pubmed: 29757195
Brain Res. 2016 Dec 1;1652:127-134
pubmed: 27725151
Prostaglandins Leukot Essent Fatty Acids. 2021 Jan;164:102219
pubmed: 33316626
Curr Dev Nutr. 2018 Jul 27;2(10):nzy065
pubmed: 30338310
Prostaglandins Other Lipid Mediat. 2014 Jun;109-111:23-31
pubmed: 24667634
Arch Gen Psychiatry. 2010 Mar;67(3):220-9
pubmed: 20194822
Int J Neuropsychopharmacol. 2017 Jul 1;20(7):575-584
pubmed: 28419244
Immunity. 2014 Mar 20;40(3):315-27
pubmed: 24656045
J Clin Psychiatry. 2022 Aug 22;83(5):
pubmed: 36005883
Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20979-84
pubmed: 18077391
Psychopharmacology (Berl). 2018 Jan;235(1):329-336
pubmed: 29090333
Am J Physiol Regul Integr Comp Physiol. 2013 Dec;305(11):R1281-96
pubmed: 24089379
Diabetes. 2013 Jun;62(6):1945-56
pubmed: 23349501
Am J Clin Nutr. 2019 May 1;109(5):1251-1263
pubmed: 31006007
Alzheimers Dement. 2015 Jan;11(1):40-50.e1-2
pubmed: 24530025
Mol Aspects Med. 2018 Dec;64:109-134
pubmed: 29305120
Epilepsia Open. 2018 May 10;3(2):255-263
pubmed: 29881804
Mol Psychiatry. 2016 Jan;21(1):71-9
pubmed: 25802980
J Am Coll Nutr. 2009 Oct;28(5):525-42
pubmed: 20439549
Circ Res. 2020 Jan 3;126(1):75-90
pubmed: 31829100
Physiol Behav. 2016 Nov 1;166:14-21
pubmed: 26703235
Nat Rev Neurosci. 2008 Jan;9(1):46-56
pubmed: 18073775
Nat Med. 2015 Mar;21(3):239-247
pubmed: 25706874
J Immunol. 2017 Aug 9;:
pubmed: 28794232
Alzheimers Dement. 2016 Jun;12(6):719-32
pubmed: 27179961
N Engl J Med. 2019 Jan 3;380(1):11-22
pubmed: 30415628
Prostaglandins Leukot Essent Fatty Acids. 2017 Apr;119:38-44
pubmed: 28410668
Front Cardiovasc Med. 2019 Feb 28;6:16
pubmed: 30873416
J Pharmacol Sci. 2018 Sep;138(1):86-88
pubmed: 30293959
Transl Psychiatry. 2019 Aug 5;9(1):190
pubmed: 31383846
Acta Psychiatr Scand. 2017 May;135(5):373-387
pubmed: 28122130
FASEB J. 2014 Nov;28(11):4835-46
pubmed: 25059230

Auteurs

Stefania Lamon-Fava (S)

Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA. stefania.lamon-fava@tufts.edu.

Minying Liu (M)

Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA.

Boadie W Dunlop (BW)

Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA.

Becky Kinkead (B)

Huntsman Mental Health Institute, Department of Psychiatry, University of Utah, Salt Lake City, UT, USA.

Pamela J Schettler (PJ)

Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA.

Jennifer C Felger (JC)

Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA.

Thomas R Ziegler (TR)

Department of Medicine, Emory University, Atlanta, GA, USA.

Maurizio Fava (M)

Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.

David Mischoulon (D)

Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.

Mark Hyman Rapaport (MH)

Huntsman Mental Health Institute, Department of Psychiatry, University of Utah, Salt Lake City, UT, USA.

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Classifications MeSH