The efficacy and safety of a duckbill-type anti-reflux metal stent as the initial metal stent for distal malignant biliary obstruction in unresectable pancreatic cancer.

anti‐reflux metal stent covered metal stent distal malignant biliary obstruction pancreatic cancer recurrent biliary obstruction

Journal

DEN open
ISSN: 2692-4609
Titre abrégé: DEN Open
Pays: Australia
ID NLM: 9918317682706676

Informations de publication

Date de publication:
Apr 2023
Historique:
received: 18 11 2022
revised: 03 12 2022
accepted: 17 12 2022
entrez: 13 1 2023
pubmed: 14 1 2023
medline: 14 1 2023
Statut: epublish

Résumé

The usefulness of duckbill-type anti-reflux metal stent (DMS) in self-expandable metal stent-naïve pancreatic cancer (PC) patients has not been well-studied. This study aimed to evaluate the efficacy and safety of DMS in such patients. We analyzed consecutive patients with unresectable PC who received a covered metal stent (CMS) as the initial self-expandable metal stent at our institution. Technical success, functional success, causes of recurrent biliary obstruction (RBO), time to RBO (TRBO), adverse events (AEs), and reintervention rates were compared between DMS and conventional CMS (c-CMS). A total of 69 patients were included (DMS: 28, c-CMS: 41). Technical success, functional success, and AEs were similar between groups. Tumor ingrowth was more common in the DMS group (18% vs. 0%, DMS was not associated with longer time to RBO compared to c-CMS in self-expandable metal stent-naïve patients.

Sections du résumé

Background UNASSIGNED
The usefulness of duckbill-type anti-reflux metal stent (DMS) in self-expandable metal stent-naïve pancreatic cancer (PC) patients has not been well-studied. This study aimed to evaluate the efficacy and safety of DMS in such patients.
Methods UNASSIGNED
We analyzed consecutive patients with unresectable PC who received a covered metal stent (CMS) as the initial self-expandable metal stent at our institution. Technical success, functional success, causes of recurrent biliary obstruction (RBO), time to RBO (TRBO), adverse events (AEs), and reintervention rates were compared between DMS and conventional CMS (c-CMS).
Results UNASSIGNED
A total of 69 patients were included (DMS: 28, c-CMS: 41). Technical success, functional success, and AEs were similar between groups. Tumor ingrowth was more common in the DMS group (18% vs. 0%,
Conclusions UNASSIGNED
DMS was not associated with longer time to RBO compared to c-CMS in self-expandable metal stent-naïve patients.

Identifiants

pubmed: 36636718
doi: 10.1002/deo2.205
pii: DEO2205
pmc: PMC9829095
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e205

Informations de copyright

© 2023 The Authors. DEN Open published by John Wiley & Sons Australia, Ltd on behalf of Japan Gastroenterological Endoscopy Society.

Déclaration de conflit d'intérêts

None.

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Auteurs

Tsuyoshi Takeda (T)

Department of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.

Takashi Sasaki (T)

Department of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.

Yuto Yamada (Y)

Department of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.
Department of Internal medicine Division of Gastroenterology and Hepatology Toho University Tokyo Japan.

Takeshi Okamoto (T)

Department of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.

Takafumi Mie (T)

Department of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.

Takaaki Furukawa (T)

Department of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.

Akiyoshi Kasuga (A)

Department of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.

Masato Matsuyama (M)

Department of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.

Masato Ozaka (M)

Department of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.

Naoki Sasahira (N)

Department of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.

Classifications MeSH