Comparative analysis of glass and Hemotek membrane feeding systems for malaria transmission research.


Journal

Transactions of the Royal Society of Tropical Medicine and Hygiene
ISSN: 1878-3503
Titre abrégé: Trans R Soc Trop Med Hyg
Pays: England
ID NLM: 7506129

Informations de publication

Date de publication:
02 06 2023
Historique:
received: 14 10 2022
revised: 28 12 2022
accepted: 29 12 2022
medline: 5 6 2023
pubmed: 14 1 2023
entrez: 13 1 2023
Statut: ppublish

Résumé

Glass membrane feeders are used in malaria research for artificial blood feeding. This study investigates the use of Hemotek membrane feeders as a standardized alternative feeding system. Hemotek feeders were compared with glass feeders by assessing mosquito feeding rate, imbibed blood meal volume and Plasmodium falciparum infection intensity on mosquito guts. While mosquito feeding rate and blood meal volume were comparable between Hemotek and glass feeders, a loss in transmission was observed using the Hemotek feeder with a conventional collagen membrane. There was no difference in transmission between both feeders when Parafilm was used as the membrane. Hemotek feeders with a Parafilm membrane can be used as an alternative feeding system for malaria transmission research.

Sections du résumé

BACKGROUND
Glass membrane feeders are used in malaria research for artificial blood feeding. This study investigates the use of Hemotek membrane feeders as a standardized alternative feeding system.
METHODS
Hemotek feeders were compared with glass feeders by assessing mosquito feeding rate, imbibed blood meal volume and Plasmodium falciparum infection intensity on mosquito guts.
RESULTS
While mosquito feeding rate and blood meal volume were comparable between Hemotek and glass feeders, a loss in transmission was observed using the Hemotek feeder with a conventional collagen membrane. There was no difference in transmission between both feeders when Parafilm was used as the membrane.
CONCLUSIONS
Hemotek feeders with a Parafilm membrane can be used as an alternative feeding system for malaria transmission research.

Identifiants

pubmed: 36637101
pii: 6986841
doi: 10.1093/trstmh/trac135
pmc: PMC10235806
doi:

Substances chimiques

Paraffin 8002-74-2

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

476-478

Informations de copyright

© The Author(s) 2023. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.

Références

BMC Res Notes. 2021 Oct 9;14(1):388
pubmed: 34627362
Parasit Vectors. 2021 Jul 7;14(1):356
pubmed: 34233734
Parasit Vectors. 2020 Aug 8;13(1):401
pubmed: 32771047
PLoS One. 2019 Nov 6;14(11):e0224268
pubmed: 31693672
Lancet Infect Dis. 2016 Jun;16(6):674-684
pubmed: 26906747

Auteurs

Wouter Graumans (W)

Department of Medical Microbiology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen 6500 HB, The Netherlands.

Michelle Schinkel (M)

Department of Medical Microbiology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen 6500 HB, The Netherlands.

Geert-Jan van Gemert (GJ)

Department of Medical Microbiology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen 6500 HB, The Netherlands.

Jeroen Spitzen (J)

Laboratory of Entomology, Wageningen University, Wageningen 6500 HB, The Netherlands.

Teun Bousema (T)

Department of Medical Microbiology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen 6500 HB, The Netherlands.
Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.

Pascal Miesen (P)

Department of Medical Microbiology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen 6500 HB, The Netherlands.

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