Validation of the CaReQoL asthma: a patient reported outcome measure for monitoring the perceived effects of pulmonary rehabilitation in adult patients with severe refractory asthma.
Asthma
Patient reported outcome measurement (PROM)
Pulmonary rehabilitation
Responsiveness
Validity
Journal
Respiratory research
ISSN: 1465-993X
Titre abrégé: Respir Res
Pays: England
ID NLM: 101090633
Informations de publication
Date de publication:
13 Jan 2023
13 Jan 2023
Historique:
received:
22
08
2022
accepted:
06
12
2022
entrez:
13
1
2023
pubmed:
14
1
2023
medline:
18
1
2023
Statut:
epublish
Résumé
The CaReQoL Asthma assesses the care-related quality of life outcomes of pulmonary rehabilitation retrospectively in patients with severe asthma. The questionnaire comprises five domains (physical functioning; social functioning; coping with asthma; knowledge about asthma; medication). To investigate construct and criterion validity of the CaReQoL Asthma, as well as its responsiveness and minimal important change (MIC), in comparison with other health measures (AQLQ, ACQ and FEV Eighty three adults with severe refractory asthma filled out the CaReQoL Asthma at 6 and 12 months after a 12-week personalized multidisciplinary pulmonary rehabilitation program in a tertiary asthma centre, either in Switzerland or The Netherlands. Construct validity and responsiveness were assessed by testing pre-defined hypotheses about associations with changes in AQLQ, ACQ and FEV Cronbach's alphas of the questionnaire domains ranged from 0.82 to 0.95. Good construct validity and responsiveness were found; 84% of the assessed correlations confirm pre-defined hypotheses and reflect both weak and moderate to strong correlations. Good criterion validity was also identified, with CaReQol scores discriminating better than other health measures between levels of GPE at 6 months post-rehabilitation. The MIC for the total score was estimated at 0.84. These study results suggest that the CaReQoL Asthma is a valid and responsive instrument and shows to be a comprehensive and tailored questionnaire for evaluating and monitoring outcomes of pulmonary rehabilitation in patients with severe refractory asthma. In order to further substantiate the reliability and validity of the CaReQoL Asthma, as well as to monitor outcomes of pulmonary rehabilitation in patients with severe asthma, it is recommended to use the CaReQoL Asthma in addition to other disease specific instruments.
Sections du résumé
BACKGROUND
BACKGROUND
The CaReQoL Asthma assesses the care-related quality of life outcomes of pulmonary rehabilitation retrospectively in patients with severe asthma. The questionnaire comprises five domains (physical functioning; social functioning; coping with asthma; knowledge about asthma; medication).
AIM
OBJECTIVE
To investigate construct and criterion validity of the CaReQoL Asthma, as well as its responsiveness and minimal important change (MIC), in comparison with other health measures (AQLQ, ACQ and FEV
METHODS
METHODS
Eighty three adults with severe refractory asthma filled out the CaReQoL Asthma at 6 and 12 months after a 12-week personalized multidisciplinary pulmonary rehabilitation program in a tertiary asthma centre, either in Switzerland or The Netherlands. Construct validity and responsiveness were assessed by testing pre-defined hypotheses about associations with changes in AQLQ, ACQ and FEV
RESULTS
RESULTS
Cronbach's alphas of the questionnaire domains ranged from 0.82 to 0.95. Good construct validity and responsiveness were found; 84% of the assessed correlations confirm pre-defined hypotheses and reflect both weak and moderate to strong correlations. Good criterion validity was also identified, with CaReQol scores discriminating better than other health measures between levels of GPE at 6 months post-rehabilitation. The MIC for the total score was estimated at 0.84.
CONCLUSION
CONCLUSIONS
These study results suggest that the CaReQoL Asthma is a valid and responsive instrument and shows to be a comprehensive and tailored questionnaire for evaluating and monitoring outcomes of pulmonary rehabilitation in patients with severe refractory asthma. In order to further substantiate the reliability and validity of the CaReQoL Asthma, as well as to monitor outcomes of pulmonary rehabilitation in patients with severe asthma, it is recommended to use the CaReQoL Asthma in addition to other disease specific instruments.
Identifiants
pubmed: 36639773
doi: 10.1186/s12931-022-02281-6
pii: 10.1186/s12931-022-02281-6
pmc: PMC9837900
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
14Informations de copyright
© 2023. The Author(s).
Références
Thorax. 1992 Feb;47(2):76-83
pubmed: 1549827
Allergy. 2019 Mar;74(3):628-630
pubmed: 30428132
J Asthma Allergy. 2017 Mar 07;10:47-56
pubmed: 28331347
Respir Med. 2005 May;99(5):553-8
pubmed: 15823451
Respir Med. 2020 Sep;171:106123
pubmed: 32846334
Eur Respir J. 2014 Feb;43(2):343-73
pubmed: 24337046
J Clin Epidemiol. 2010 Jul;63(7):760-766.e1
pubmed: 20056385
J Clin Epidemiol. 2007 Jan;60(1):34-42
pubmed: 17161752
J Clin Epidemiol. 1994 Jan;47(1):81-7
pubmed: 8283197
J Allergy Clin Immunol Pract. 2016 Jan-Feb;4(1):130-41
pubmed: 26563672
Health Expect. 2017 Feb;20(1):11-23
pubmed: 26889874
Chest. 1999 May;115(5):1265-70
pubmed: 10334138
BMJ. 2013 Jan 28;346:f167
pubmed: 23358487
Eur Respir J. 1999 Oct;14(4):902-7
pubmed: 10573240
Qual Life Res. 2015 Mar;24(3):631-9
pubmed: 25201169
Cochrane Database Syst Rev. 2017 Mar 13;3:CD012286
pubmed: 28288272
J Allergy Clin Immunol. 2015 Apr;135(4):896-902
pubmed: 25441637
Am J Respir Crit Care Med. 2013 Oct 15;188(8):e13-64
pubmed: 24127811
Health Qual Life Outcomes. 2020 May 27;18(1):157
pubmed: 32460896
Respirology. 2019 Sep;24(9):828-829
pubmed: 30806003
BMC Pulm Med. 2019 Jul 24;19(1):134
pubmed: 31340793
Respirology. 2019 Sep;24(9):916-917
pubmed: 31307112
Eur Respir J. 2012 Dec;40(6):1324-43
pubmed: 22743675
Qual Life Res. 2003 Jun;12(4):349-62
pubmed: 12797708
Health Qual Life Outcomes. 2010 Jul 10;8:65
pubmed: 20618978