Labelling Matrix Metalloproteinases.
Matrix metalloproteinase
biological targeting
fluorescent probe
protein labelling
radioactive labelling
zinc-containing proteases
Journal
Current medicinal chemistry
ISSN: 1875-533X
Titre abrégé: Curr Med Chem
Pays: United Arab Emirates
ID NLM: 9440157
Informations de publication
Date de publication:
2023
2023
Historique:
received:
02
09
2022
revised:
05
12
2022
accepted:
18
12
2022
medline:
27
6
2023
pubmed:
17
1
2023
entrez:
16
1
2023
Statut:
ppublish
Résumé
Matrix metalloproteinases (MMPs) are a family of zinc-containing proteases that participate in many physiological and pathological processes in vivo. Recently, the MMP network has been established according to a deeper understanding of its functions. Some MMPs have been also regarded as biomarkers of various diseases, including inflammation, nerve diseases, and cancers. MMP labelling has been thus paid more attention in recent decades. Accordingly, both reagents and technologies for MMP labelling have been rapidly developed. Here we summarize the recent development of some MMP labelling methods. This review was identified through keyword (MMPs; labelling; etc.) searches in the ScienceDirect database, Scifinder, Web of Science, and PubMed for which typical cases were used for an inductive overview. In spite of the advances in MMP labelling, selective labelling of a specific MMP is still an open issue. We hope that this article can be helpful in developing specific MMP labelling methods in future.
Identifiants
pubmed: 36642878
pii: CMC-EPUB-128845
doi: 10.2174/0929867330666230113121728
doi:
Substances chimiques
Matrix Metalloproteinases
EC 3.4.24.-
Types de publication
Review
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4569-4585Informations de copyright
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