Comparison of Perfluorocarbon Liquids Cytotoxicity Tests: Direct Contact Versus the Test on Liquid Extracts.


Journal

ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658

Informations de publication

Date de publication:
10 Jan 2023
Historique:
received: 25 07 2022
accepted: 14 12 2022
entrez: 16 1 2023
pubmed: 17 1 2023
medline: 17 1 2023
Statut: epublish

Résumé

The purpose of this study is to compare the in vitro cytotoxicity tests according to the ISO 10993-5 (2009) standards using direct contact and the test on liquid extracts of compounds previously identified as possible toxic impurities in perfluorocarbon liquids (PFCLs) for use in vitreoretinal surgery. Compounds including perfluorooctanoic acid (PFOA), 1

Identifiants

pubmed: 36643447
doi: 10.1021/acsomega.2c04697
pmc: PMC9835178
doi:

Types de publication

Journal Article

Langues

eng

Pagination

365-372

Informations de copyright

© 2022 The Authors. Published by American Chemical Society.

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

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Auteurs

Claudio Gatto (C)

Research and Development Department of AL.CHI.MI.A. S.r.l., Ponte San Nicolò (PD)35020, Italy.

Paolo Ruzza (P)

Institute of Biomolecular Chemistry of CNR, Padua Unit, Via F. Marzolo 1, Padua35131, Italy.

Laura Giurgola (L)

Research and Development Department of AL.CHI.MI.A. S.r.l., Ponte San Nicolò (PD)35020, Italy.

Claudia Honisch (C)

Institute of Biomolecular Chemistry of CNR, Padua Unit, Via F. Marzolo 1, Padua35131, Italy.

Orietta Rossi (O)

Research and Development Department of AL.CHI.MI.A. S.r.l., Ponte San Nicolò (PD)35020, Italy.

Mario R Romano (MR)

Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, Milano20090, Italy.

Eugenio Ragazzi (E)

Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Largo Meneghetti 2, Padua35131, Italy.

Jana D'Amato Tóthová (J)

Research and Development Department of AL.CHI.MI.A. S.r.l., Ponte San Nicolò (PD)35020, Italy.

Classifications MeSH