New aspects of TGF-β superfamily signaling in development and disease (2022 FASEB meeting review).
Receptors
Smads
Structures
TGF-β
Therapeutics
Journal
Faculty reviews
ISSN: 2732-432X
Titre abrégé: Fac Rev
Pays: England
ID NLM: 101769226
Informations de publication
Date de publication:
2022
2022
Historique:
entrez:
16
1
2023
pubmed:
17
1
2023
medline:
17
1
2023
Statut:
epublish
Résumé
The 13th Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference, "TGF-β superfamily signaling in development and disease" was convened at the Grand Hotel in Malahide, Ireland in July 2022. The Transforming Growth Factor-β (TGF-β) family of secreted proteins consists of agents of intercellular communication found in all multicellular animals. Attending the meeting was a diverse group of scholars with shared interests in understanding TGF-β signaling mechanisms, normal functions, and the diseases associated with misregulation and mutation. Despite intense study over the previous 35 years, new features of TGF-β activity continue to be discovered. This meeting report offers 21 investigator-provided summaries that illustrate the breadth of the thought-provoking presentations. An emerging theme of the meeting was the power of cross-disciplinary studies, such as one combining immunology, biochemistry, and structural biology, to unravel the secrets of parasitic TGF-β mimics. Please join us at the next meeting.
Identifiants
pubmed: 36644295
doi: 10.12703/r/11-36
pmc: PMC9816873
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
36Subventions
Organisme : NIH HHS
ID : R24 OD028242
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM118029
Pays : United States
Informations de copyright
Copyright: © 2022 O’Connor MB et al.
Déclaration de conflit d'intérêts
The authors declare that they have no competing interests.No competing interests were disclosed.No competing interests were disclosed.No competing interests were disclosed.
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