Cortical Thickness and Brain Glucose Metabolism in Healthy Aging.

FDG MRI brain glucose metabolism cortical thickness healthy aging

Journal

Journal of clinical neurology (Seoul, Korea)
ISSN: 1738-6586
Titre abrégé: J Clin Neurol
Pays: Korea (South)
ID NLM: 101252374

Informations de publication

Date de publication:
Mar 2023
Historique:
received: 10 01 2022
revised: 04 08 2022
accepted: 07 08 2022
pubmed: 18 1 2023
medline: 18 1 2023
entrez: 17 1 2023
Statut: ppublish

Résumé

We aimed to determine the effect of demographic factors on cortical thickness and brain glucose metabolism in healthy aging subjects. The following tests were performed on 71 subjects with normal cognition: neurological examination, 3-tesla magnetic resonance imaging, Age was negatively correlated with the mean cortical thickness in all lobes (frontal and parietal lobes, Age and sex affect cortical thickness and brain glucose metabolism in different ways. Demographic factors must therefore be considered in analyses of cortical thickness and brain metabolism.

Sections du résumé

BACKGROUND AND PURPOSE OBJECTIVE
We aimed to determine the effect of demographic factors on cortical thickness and brain glucose metabolism in healthy aging subjects.
METHODS METHODS
The following tests were performed on 71 subjects with normal cognition: neurological examination, 3-tesla magnetic resonance imaging,
RESULTS RESULTS
Age was negatively correlated with the mean cortical thickness in all lobes (frontal and parietal lobes,
CONCLUSIONS CONCLUSIONS
Age and sex affect cortical thickness and brain glucose metabolism in different ways. Demographic factors must therefore be considered in analyses of cortical thickness and brain metabolism.

Identifiants

pubmed: 36647225
pii: 19.e2
doi: 10.3988/jcn.2022.0021
pmc: PMC9982173
doi:

Types de publication

Journal Article

Langues

eng

Pagination

138-146

Subventions

Organisme : Eisai Korea
Pays : Korea

Informations de copyright

Copyright © 2023 Korean Neurological Association.

Déclaration de conflit d'intérêts

The authors have no potential conflicts of interest to disclose.

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Auteurs

Kyoungwon Baik (K)

Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.

Seun Jeon (S)

Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.

Soh-Jeong Yang (SJ)

Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.

Yeona Na (Y)

Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.

Seok Jong Chung (SJ)

Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.

Han Soo Yoo (HS)

Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.

Mijin Yun (M)

Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul, Korea.

Phil Hyu Lee (PH)

Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.

Young H Sohn (YH)

Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.

Byoung Seok Ye (BS)

Department of Neurology, Yonsei University College of Medicine, Seoul, Korea. romel79@gmail.com.

Classifications MeSH