Catalyst-Free Thia-Michael Addition to α-Trifluoromethylacrylates for 3D Network Synthesis.

DFT calculations Michael addition fluorine effect kinetics thermosets

Journal

Chemistry (Weinheim an der Bergstrasse, Germany)
ISSN: 1521-3765
Titre abrégé: Chemistry
Pays: Germany
ID NLM: 9513783

Informations de publication

Date de publication:
06 Apr 2023
Historique:
received: 28 11 2022
medline: 18 1 2023
pubmed: 18 1 2023
entrez: 17 1 2023
Statut: ppublish

Résumé

Thia-Michael additions (1,4-additions of a thiol to a Michael acceptor) are generally catalyzed by an external Brønsted or Lewis base. A spontaneous (uncatalyzed) Michael addition of thiols to α-trifluoromethyl acrylates is described, as well as its application to the very efficient preparation of a thermoset. A thorough mechanistic investigation, based on an experimental kinetic study and on DFT calculations, is presented for the addition of arene- and alkanethiols to tert-butyl trifluoromethyl acrylate in polar aprotic solvents, unveiling a probable solvent-assisted proton transfer in the rate-determining step and a considerable lowering of the energy barrier induced by the CF

Identifiants

pubmed: 36647801
doi: 10.1002/chem.202203712
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e202203712

Subventions

Organisme : Agence Nationale de la Recherche
ID : ANR-19-CE06-0014

Informations de copyright

© 2023 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH.

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Auteurs

Dimitri Berne (D)

ICGM, Univ Montpellier, CNRS, ENSCM, Montpellier, France.

Sébastien Lemouzy (S)

ICGM, Univ Montpellier, CNRS, ENSCM, Montpellier, France.

Pascale Guiffrey (P)

ICGM, Univ Montpellier, CNRS, ENSCM, Montpellier, France.

Sylvain Caillol (S)

ICGM, Univ Montpellier, CNRS, ENSCM, Montpellier, France.

Vincent Ladmiral (V)

ICGM, Univ Montpellier, CNRS, ENSCM, Montpellier, France.

Eric Manoury (E)

CNRS, LCC (Laboratoire de Chimie de Coordination), UPS, INPT, Université de Toulouse, 205 route de Narbonne, 31077, Toulouse, Cedex 4, France.

Rinaldo Poli (R)

CNRS, LCC (Laboratoire de Chimie de Coordination), UPS, INPT, Université de Toulouse, 205 route de Narbonne, 31077, Toulouse, Cedex 4, France.
Institut Universitaire de France, 1, rue Descartes, 75231, Paris, France.

Eric Leclerc (E)

ICGM, Univ Montpellier, CNRS, ENSCM, Montpellier, France.

Classifications MeSH