Axonal membrane stretch suppresses neuronal excitability by activating mechanosensitive K2P channels at the node of Ranvier.
Action potential
Membrane stretch
Node of Ranvier
Single-channel activity
Two-pore-domain potassium channels
Journal
Molecular brain
ISSN: 1756-6606
Titre abrégé: Mol Brain
Pays: England
ID NLM: 101468876
Informations de publication
Date de publication:
17 01 2023
17 01 2023
Historique:
received:
15
11
2022
accepted:
10
01
2023
entrez:
17
1
2023
pubmed:
18
1
2023
medline:
20
1
2023
Statut:
epublish
Résumé
Saltatory conduction is the propagation of action potentials along myelinated nerves, which enables fast propagation through the node of Ranvier. Recently, we demonstrated that K2P channels, TWIK-related K
Identifiants
pubmed: 36650581
doi: 10.1186/s13041-023-01000-6
pii: 10.1186/s13041-023-01000-6
pmc: PMC9843873
doi:
Substances chimiques
Arachidonic Acid
27YG812J1I
Potassium Channels, Tandem Pore Domain
0
potassium channel protein TREK-1
0
Kcnk4 protein, rat
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
8Informations de copyright
© 2023. The Author(s).
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