Short Course of Antifungal Therapy in Patients With Uncomplicated

90-day mortality prolonged course recurrent Candida BSI short course uncomplicated candidemia

Journal

Open forum infectious diseases
ISSN: 2328-8957
Titre abrégé: Open Forum Infect Dis
Pays: United States
ID NLM: 101637045

Informations de publication

Date de publication:
Jan 2023
Historique:
received: 20 06 2022
accepted: 06 12 2022
entrez: 19 1 2023
pubmed: 20 1 2023
medline: 20 1 2023
Statut: epublish

Résumé

The objective of this study was to compare the clinical outcomes of patients receiving a short course (SC) vs a prolonged course (PC) of antifungal therapy for uncomplicated All episodes of uncomplicated A total of 114 patients with uncomplicated Receiving a short vs prolonged course of antifungal therapy did not affect mortality or BSI recurrence in patients with uncomplicated candidemia.

Sections du résumé

Background UNASSIGNED
The objective of this study was to compare the clinical outcomes of patients receiving a short course (SC) vs a prolonged course (PC) of antifungal therapy for uncomplicated
Methods UNASSIGNED
All episodes of uncomplicated
Results UNASSIGNED
A total of 114 patients with uncomplicated
Conclusions UNASSIGNED
Receiving a short vs prolonged course of antifungal therapy did not affect mortality or BSI recurrence in patients with uncomplicated candidemia.

Identifiants

pubmed: 36655192
doi: 10.1093/ofid/ofac656
pii: ofac656
pmc: PMC9835756
doi:

Types de publication

Journal Article

Langues

eng

Pagination

ofac656

Informations de copyright

© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

Déclaration de conflit d'intérêts

Potential conflicts of interest. Outside the submitted work, D.R.G. reports investigator-initiated grants from Pfizer Inc., Shionogi, and Gilead Italia. Outside the submitted work, M.B. reports research grants and/or personal fees for advisor/consultant and/or speaker/chairman from Bayer, BioMérieux, Cidara, Cipla, Gilead, Menarini, MSD, Pfizer, and Shionogi. Outside the submitted work, A.V. has participated on advisory boards and/or received speaker fees from Angelini, Menarini, Merck Sharp and Dohme, Pfizer, and Shionogi. He has also received study grants from Merck Sharp and Dohme and Astellas. All other authors report no potential conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.

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Auteurs

Antonio Vena (A)

Infectious Diseases Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.
Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.

Francesca Bovis (F)

Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Biostatistics Unit, University of Genoa, Genoa, Italy.

Stefania Tutino (S)

Infectious Diseases Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Alessandro Santagostino Barbone (A)

Infectious Diseases Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Laura Mezzogori (L)

Infectious Diseases Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Marta Ponzano (M)

Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Biostatistics Unit, University of Genoa, Genoa, Italy.

Lucia Taramasso (L)

Infectious Diseases Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Federico Baldi (F)

Infectious Diseases Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Silvia Dettori (S)

Infectious Diseases Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Laura Labate (L)

Infectious Diseases Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Chiara Russo (C)

Infectious Diseases Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Daniele Roberto Giacobbe (DR)

Infectious Diseases Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.
Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.

Malgorzata Mikulska (M)

Infectious Diseases Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.
Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.

Chiara Dentone (C)

Infectious Diseases Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Laura Magnasco (L)

Infectious Diseases Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Anna Marchese (A)

Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.
Microbiology Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Chiara Robba (C)

Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.
Anesthesia and Intensive Care, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Lorenzo Ball (L)

Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.
Anesthesia and Intensive Care, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Denise Battaglini (D)

Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.
Anesthesia and Intensive Care, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Paolo Pelosi (P)

Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.
Anesthesia and Intensive Care, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Francesca Crea (F)

Microbiology Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Vincenzo Di Pilato (V)

Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.
Microbiology Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.

Antonio Di Biagio (A)

Infectious Diseases Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.
Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.

Emilio Bouza (E)

Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Instituto de Investigación Sanitaria Hospital Gregorio Marañón, Madrid, Spain.
CIBER Enfermedades Respiratorias-CIBERES (CB06/06/0058), Madrid, Spain.
Medicine Department, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.

Patricia Muñoz (P)

Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Instituto de Investigación Sanitaria Hospital Gregorio Marañón, Madrid, Spain.
CIBER Enfermedades Respiratorias-CIBERES (CB06/06/0058), Madrid, Spain.
Medicine Department, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.

Matteo Bassetti (M)

Infectious Diseases Unit, Policlinico San Martino Hospital-IRCCS, Genoa, Italy.
Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.

Classifications MeSH