Endothelial contraction of retinal veins.

Swine Animals Retinal Vein Endothelin-1 Endothelial Cells Retinal Artery / physiology Endothelium, Vascular Contractile Proteins Muscle Contraction Endothelins / pharmacology
Endothelin-1 Endothelium Porcine Retinal veins Vasoactivity

Journal

Experimental eye research
ISSN: 1096-0007
Titre abrégé: Exp Eye Res
Pays: England
ID NLM: 0370707

Informations de publication

Date de publication:
03 2023
Historique:
received: 22 08 2022
revised: 14 12 2022
accepted: 09 01 2023
pubmed: 20 1 2023
medline: 3 3 2023
entrez: 19 1 2023
Statut: ppublish

Résumé

We have previously reported that porcine retinal veins can be contracted by vasoactive factors such as endothelin-1, but it is still unknown which cells play the major role in such contraction responses. This study seeks to confirm whether retinal vein endothelial cells play a significant role in the endothelin-1 induced contraction of porcine retinal veins. This is a novel study which provides confirmation of the endothelial cells' ability to contract retinal veins using a live vessel preparation. Retinal veins were isolated from porcine retina and cannulated for perfusion. The vessels were exposed to extraluminal delivery of endothelin-1 (10

Identifiants

DOI: 10.1016/j.exer.2023.109386 PMID: 36657697
pubmed: 36657697
pii: S0014-4835(23)00007-6
doi: 10.1016/j.exer.2023.109386
pii:
doi:

Substances chimiques

Endothelin-1 0
Contractile Proteins 0
Endothelins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

109386

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.

Auteurs

Dao-Yi Yu (DY)

Lions Eye Institute, Perth, Western Australia, Australia; Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Western Australia, Australia. Electronic address: dao-yi.yu@uwa.edu.au.

Er-Ning Su (EN)

Lions Eye Institute, Perth, Western Australia, Australia; Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Western Australia, Australia.

Andrew Mehnert (A)

Lions Eye Institute, Perth, Western Australia, Australia; Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Western Australia, Australia.

Paula K Yu (PK)

Lions Eye Institute, Perth, Western Australia, Australia; Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Western Australia, Australia.

Stephen J Cringle (SJ)

Lions Eye Institute, Perth, Western Australia, Australia; Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Western Australia, Australia.

William H Morgan (WH)

Lions Eye Institute, Perth, Western Australia, Australia; Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Western Australia, Australia.

Ian L McAllister (IL)

Lions Eye Institute, Perth, Western Australia, Australia; Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Western Australia, Australia.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Artiodactyla › Suidae › Endothelial contraction of retinal veins.
questionsmedicales.fr › Eucaryotes › Animaux › Endothelial contraction of retinal veins.
questionsmedicales.fr › Système cardiovasculaire › Vaisseaux sanguins › Veines › Veine centrale de la rétine › Endothelial contraction of retinal veins.
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Endothélines › Endothéline-1 › Endothelial contraction of retinal veins.
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules endothéliales › Endothelial contraction of retinal veins.
questionsmedicales.fr › Système cardiovasculaire › Vaisseaux sanguins › Vaisseaux rétiniens › Artère centrale de la rétine › Endothelial contraction of retinal veins.
questionsmedicales.fr › Tissus › Épithélium › Endothélium › Endothélium vasculaire › Endothelial contraction of retinal veins.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines contractiles › Endothelial contraction of retinal veins.
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Contraction musculaire › Endothelial contraction of retinal veins.
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Endothélines › Endothelial contraction of retinal veins.