Osteonecrosis of the Jaw.
drug-induced osteonecrosis
osteonecrosis
osteoradionecrosis
radiotherapy
Journal
Dentistry journal
ISSN: 2304-6767
Titre abrégé: Dent J (Basel)
Pays: Switzerland
ID NLM: 101716125
Informations de publication
Date de publication:
09 Jan 2023
09 Jan 2023
Historique:
received:
23
11
2022
revised:
30
12
2022
accepted:
05
01
2023
entrez:
20
1
2023
pubmed:
21
1
2023
medline:
21
1
2023
Statut:
epublish
Résumé
Osteonecrosis of the jaw is a condition in which bone cells die due to various causes. It is classified as drug-induced jaw osteonecrosis, osteoradionecrosis, traumatic, non-traumatic, and spontaneous osteonecrosis. Antiresorptive or antiangiogenic drugs cause drug-induced osteonecrosis. The combination of medications, microbial contamination, and local trauma induces this condition. Osteoradionecrosis is a severe radiation therapy side effect that can affect people with head and neck cancer. It is described as an exposed bone area that does not heal for longer than three months after the end of radiation treatment with the absence of any indications of an original tumor, recurrence, or metastasis. Trauma (tooth extraction), tumor site, radiation dose that the patient receives, the area of the bone which is irradiated, oral hygiene, and other factors are risk factors for the development of osteonecrosis. Less frequently, osteonecrosis can also be induced by non-traumatic and traumatic causes. Non-traumatic osteonecrosis is brought on by infections, acquired and congenital disorders, as well as the impact of chemicals. Traumatic osteonecrosis is brought on by thermal, mechanical, or chemical damage. The treatment of osteonecrosis can be conservative, which aims to be beneficial for the patient's quality of life, and surgical, which involves debridement of the necrotic bone.
Identifiants
pubmed: 36661560
pii: dj11010023
doi: 10.3390/dj11010023
pmc: PMC9858620
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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