Data From a One-Stop-Shop Comprehensive Cancer Screening Center.


Journal

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
ISSN: 1527-7755
Titre abrégé: J Clin Oncol
Pays: United States
ID NLM: 8309333

Informations de publication

Date de publication:
10 05 2023
Historique:
medline: 8 5 2023
pubmed: 21 1 2023
entrez: 20 1 2023
Statut: ppublish

Résumé

Cancer is the second leading cause of death globally. However, by implementing evidence-based prevention strategies, 30%-50% of cancers can be detected early with improved outcomes. At the integrated cancer prevention center (ICPC), we aimed to increase early detection by screening for multiple cancers during one visit. Self-referred asymptomatic individuals, age 20-80 years, were included prospectively. Clinical, laboratory, and epidemiological data were obtained by multiple specialists, and further testing was obtained based on symptoms, family history, individual risk factors, and abnormalities identified during the visit. Follow-up recommendations and diagnoses were given as appropriate. Between January 1, 2006, and December 31, 2019, 8,618 men and 8,486 women, average age 47.11 ± 11.71 years, were screened. Of 259 cancers detected through the ICPC, 49 (19.8%) were stage 0, 113 (45.6%) stage I, 30 (12.1%) stage II, 25 (10.1%) stage III, and 31(12.5%) stage IV. Seventeen cancers were missed, six of which were within the scope of the ICPC. Compared with the Israeli registry, at the ICPC, less cancers were diagnosed at a metastatic stage for breast (none We present a proof of concept study for a one-stop-shop approach to cancer screening in a multidisciplinary outpatient clinic. We successfully detected cancers at an early stage, which has the potential to reduce morbidity and mortality as well as offer substantial cost savings.[Media: see text].

Identifiants

pubmed: 36669135
doi: 10.1200/JCO.22.00938
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2503-2510

Commentaires et corrections

Type : CommentIn

Auteurs

Ezra Bernstein (E)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.
NYU Langone Medical Center, New York, NY.

Shahar Lev-Ari (S)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Shiran Shapira (S)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Ari Leshno (A)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Udi Sommer (U)

Tel Aviv University Faculty of Social Sciences, School of Political Science, Government and International Relations, Tel Aviv, Israel.

Humaid Al-Shamsi (H)

Burjeel Cancer Institute, University of Sharjah, Sharjah, United Arab Emirates.

Meital Shaked (M)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.

Ori Segal (O)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.

Lior Galazan (L)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.

Mori Hay-Levy (M)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.

Miri Sror (M)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.

Amira Harlap-Gat (A)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.

Michael Peer (M)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Menachem Moshkowitz (M)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Ido Wolf (I)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Department of Oncology, Tel Aviv Medical Center, Tel Aviv, Israel.

Eliezer Liberman (E)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Gil Shenberg (G)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.

Eyal Gur (E)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Department of Plastic and Reconstructive Surgery, Tel Aviv Medical Center, Tel Aviv, Israel.

Hanoch Elran (H)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.
Department of Neurosurgery, Tel Aviv Medical Center, Tel Aviv, Israel.

Gustavo Melinger (G)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
The Gynecological and Obstetric Ultrasound Unit, Tel Aviv Medical Center, Tel Aviv, Israel.

Jacob Mashiah (J)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Division of Dermatology and Venerology, Tel Aviv Medical Center, Tel Aviv, Israel.

Ofer Isakov (O)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Institute of Gastrointestinal and Liver Diseases, Tel Aviv Medical Center, Tel Aviv, Israel.

Elad Zrifin (E)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.
Oral and Maxillofacial Surgery Unit, Otolaryngology-Head and Neck Surgery, Tel Aviv Medical Center, Tel Aviv, Israel.

Nathan Gluck (N)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Institute of Gastrointestinal and Liver Diseases, Tel Aviv Medical Center, Tel Aviv, Israel.

Roy Dekel (R)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Institute of Gastrointestinal and Liver Diseases, Tel Aviv Medical Center, Tel Aviv, Israel.

Shlomi Kleinman (S)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Oral and Maxillofacial Surgery Unit, Otolaryngology-Head and Neck Surgery, Tel Aviv Medical Center, Tel Aviv, Israel.

Galit Aviram (G)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Department of Radiology, Tel Aviv Medical Center, Tel Aviv, Israel.

Arye Blachar (A)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Department of Radiology, Tel Aviv Medical Center, Tel Aviv, Israel.

Ada Kessler (A)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Department of Radiology, Tel Aviv Medical Center, Tel Aviv, Israel.

Orit Golan (O)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Department of Radiology, Tel Aviv Medical Center, Tel Aviv, Israel.

Ravit Geva (R)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Department of Oncology, Tel Aviv Medical Center, Tel Aviv, Israel.

Ofer Yossepowitch (O)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Department of Urology, Tel Aviv Medical Center, Tel Aviv, Israel.

Alfred I Neugut (AI)

Columbia University Medical Center, Herbert Irving Comprehensive Cancer Center, New York, NY.

Nadir Arber (N)

Health Promotion and Integrated Cancer Prevention Center, Tel Aviv Medical Center, Tel Aviv, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Institute of Gastrointestinal and Liver Diseases, Tel Aviv Medical Center, Tel Aviv, Israel.

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