Genetic Predisposition to Neurological Complications in Patients with COVID-19.
COVID-19
genetic predisposition
neurological complications
optical genome mapping
rare SVs
Journal
Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414
Informations de publication
Date de publication:
09 01 2023
09 01 2023
Historique:
received:
25
11
2022
revised:
03
01
2023
accepted:
03
01
2023
entrez:
21
1
2023
pubmed:
22
1
2023
medline:
25
1
2023
Statut:
epublish
Résumé
Several studies have identified rare and common genetic variants associated with severe COVID-19, but no study has reported genetic determinants as predisposition factors for neurological complications. In this report, we identified rare/unique structural variants (SVs) implicated in neurological functions in two individuals with neurological manifestations of COVID-19. This report highlights the possible genetic link to the neurological symptoms with COVID-19 and calls for a collective effort to study these cohorts for a possible genetic linkage.
Identifiants
pubmed: 36671517
pii: biom13010133
doi: 10.3390/biom13010133
pmc: PMC9855758
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NICHD NIH HHS
ID : P50 HD105351
Pays : United States
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