Recombinant Protein Vaccines against Human Betacoronaviruses: Strategies, Approaches and Progress.
COVID-19
MERS-CoV
RBD
S protein
SARS-CoV
SARS-CoV-2
adjuvants
human betacoronaviruses
multi-epitope vaccines
recombinant protein vaccines
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
15 Jan 2023
15 Jan 2023
Historique:
received:
11
11
2022
revised:
12
01
2023
accepted:
12
01
2023
entrez:
21
1
2023
pubmed:
22
1
2023
medline:
25
1
2023
Statut:
epublish
Résumé
Betacoronaviruses have already troubled humanity more than once. In 2002-2003 and 2012, the SARS-CoV and MERS-CoV, respectively, caused outbreaks of respiratory syndromes with a fatal outcome. The spread of the SARS-CoV-2 coronavirus has become a pandemic. These three coronaviruses belong to the genus Betacoronavirus and have a zoonotic origin. The emergence of new coronavirus infections in the future cannot be ruled out, and vaccination is the main way to prevent the spread of the infection. Previous experience in the development of vaccines against SARS and MERS has helped to develop a number of vaccines against SARS-CoV-2 in a fairly short time. Among them, there are quite a few recombinant protein vaccines, which seem to be very promising in terms of safety, minimization of side effects, storage and transportation conditions. The problem of developing a universal betacoronavirus vaccine is also still relevant. Here, we summarize the information on the designing of vaccines based on recombinant proteins against highly pathogenic human betacoronaviruses SARS-CoV, MERS-CoV and SARS-CoV-2.
Identifiants
pubmed: 36675218
pii: ijms24021701
doi: 10.3390/ijms24021701
pmc: PMC9863728
pii:
doi:
Substances chimiques
COVID-19 Vaccines
0
Recombinant Proteins
0
Vaccines, Synthetic
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Russian Foundation for Basic Research
ID : 21-34-70004
Références
Infect Genet Evol. 2020 Nov;85:104502
pubmed: 32798769
Emerg Microbes Infect. 2022 Dec;11(1):2724-2734
pubmed: 36287714
Nature. 2020 Aug;584(7821):437-442
pubmed: 32555388
J Biomol Struct Dyn. 2021 May;39(8):2857-2872
pubmed: 32295479
Cell Res. 2021 Sep;31(9):1011-1023
pubmed: 34267349
Science. 2020 Mar 13;367(6483):1260-1263
pubmed: 32075877
Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):E7348-E7357
pubmed: 28807998
Biochim Biophys Acta Gen Subj. 2021 Jun;1865(6):129893
pubmed: 33731300
EClinicalMedicine. 2022 Apr;46:101383
pubmed: 35434578
Clin Microbiol Infect. 2022 Sep;28(9):1263-1271
pubmed: 35436611
Pharmaceutics. 2022 Apr 06;14(4):
pubmed: 35456639
Infez Med. 2020 Ahead of print Jun 1;28(2):174-184
pubmed: 32275259
NPJ Vaccines. 2021 Dec 13;6(1):151
pubmed: 34903722
EBioMedicine. 2020 May;55:102743
pubmed: 32249203
Hum Vaccin Immunother. 2023 Dec 31;19(1):2203632
pubmed: 37113012
J Virol. 2006 Jan;80(2):941-50
pubmed: 16378996
J Biomed Sci. 2020 Dec 20;27(1):104
pubmed: 33341119
Lancet Infect Dis. 2021 Aug;21(8):1107-1119
pubmed: 33773111
Vaccine. 2014 Apr 11;32(18):2100-8
pubmed: 24560617
Nat Commun. 2021 Sep 1;12(1):5215
pubmed: 34471122
Hum Vaccin Immunother. 2021 Aug 3;17(8):2356-2366
pubmed: 33847226
Microb Pathog. 2020 Aug;145:104236
pubmed: 32376359
PLoS One. 2013 Dec 04;8(12):e81587
pubmed: 24324708
Nat Med. 2020 Sep;26(9):1422-1427
pubmed: 32651581
Cell. 2020 Nov 25;183(5):1367-1382.e17
pubmed: 33160446
Sci Transl Med. 2022 Feb 16;14(632):eabi5735
pubmed: 34914540
Curr Top Microbiol Immunol. 2018;419:1-42
pubmed: 28643204
Lancet Infect Dis. 2021 Sep;21(9):1257-1270
pubmed: 33887209
Vaccine. 2007 Jan 8;25(4):729-40
pubmed: 17049691
Inflamm Regen. 2020 Dec 21;40(1):41
pubmed: 33349265
Vaccine. 2009 Aug 6;27(36):5001-7
pubmed: 19523911
Vaccine. 2022 Jul 29;40(31):4220-4230
pubmed: 35691871
Vaccine. 2018 Mar 27;36(14):1853-1862
pubmed: 29496347
Front Microbiol. 2022 Feb 28;13:845316
pubmed: 35295298
J Clin Microbiol. 2005 Aug;43(8):3718-26
pubmed: 16081901
Nat Rev Immunol. 2007 Sep;7(9):715-25
pubmed: 17703228
Trends Mol Med. 2020 May;26(5):483-495
pubmed: 32359479
Nat Rev Immunol. 2008 Jan;8(1):34-47
pubmed: 18064051
Front Plant Sci. 2021 May 13;12:682953
pubmed: 34054909
Viruses. 2019 Mar 02;11(3):
pubmed: 30832356
Nature. 2020 Oct;586(7830):572-577
pubmed: 32726802
Front Mol Biosci. 2020 Sep 01;7:226
pubmed: 33033717
Viruses. 2020 Feb 25;12(3):
pubmed: 32106567
Nature. 2021 Jun;594(7862):253-258
pubmed: 33873199
Nat Commun. 2015 Jul 28;6:7712
pubmed: 26218507
J Virol. 2011 Dec;85(23):12201-15
pubmed: 21937658
Nucleic Acids Res. 2000 Jan 1;28(1):235-42
pubmed: 10592235
Cell. 2020 Nov 12;183(4):1043-1057.e15
pubmed: 32970989
Viral Immunol. 2013 Apr;26(2):126-32
pubmed: 23573979
Mol Biomed. 2021;2(1):29
pubmed: 34766005
Cell Mol Immunol. 2016 Mar;13(2):180-90
pubmed: 25640653
DNA Cell Biol. 2005 Aug;24(8):510-5
pubmed: 16101349
J Virol. 2015 Mar;89(6):2995-3007
pubmed: 25520500
Vaccines (Basel). 2021 Nov 17;9(11):
pubmed: 34835277
Cell Rep. 2021 Dec 21;37(12):110143
pubmed: 34919799
Sci Adv. 2021 Jan 1;7(1):
pubmed: 33277323
Expert Rev Anti Infect Ther. 2020 Dec;18(12):1201-1211
pubmed: 32749914
Cell Mol Immunol. 2020 Sep;17(9):998-1000
pubmed: 32728199
J Virol. 2006 Jun;80(12):5757-67
pubmed: 16731915
Nat Rev Immunol. 2021 Feb;21(2):73-82
pubmed: 33340022
Cell. 2020 Aug 6;182(3):722-733.e11
pubmed: 32645327
EBioMedicine. 2022 Jun;80:104062
pubmed: 35594660
PLoS One. 2012;7(11):e50366
pubmed: 23185609
Inform Med Unlocked. 2020;19:100338
pubmed: 32352026
Nat Commun. 2021 Mar 1;12(1):1346
pubmed: 33649323
Emerg Microbes Infect. 2022 Dec;11(1):1910-1919
pubmed: 35686572
Vaccine. 2017 Jan 3;35(1):10-18
pubmed: 27899228
N Engl J Med. 2021 Sep 23;385(13):1172-1183
pubmed: 34192426
Lancet. 2021 Feb 20;397(10275):682-694
pubmed: 33524311
Front Immunol. 2020 Oct 07;11:576622
pubmed: 33117378
Ann Clin Microbiol Antimicrob. 2021 Jan 18;20(1):8
pubmed: 33461573
Hong Kong Med J. 2012 Feb;18 Suppl 2:31-6
pubmed: 22311359
EBioMedicine. 2022 Sep;83:104217
pubmed: 35970020
Vaccines (Basel). 2021 Nov 17;9(11):
pubmed: 34835278
Lancet. 2022 Jan 29;399(10323):461-472
pubmed: 35065705
Expert Rev Vaccines. 2002 Jun;1(1):111-8
pubmed: 12908518
Nat Commun. 2020 Jul 14;11(1):3581
pubmed: 32665645
Hum Vaccin Immunother. 2015;11(5):1244-50
pubmed: 25874632
J Immunol Res. 2016;2016:1459394
pubmed: 27274998
Nature. 2022 Jan;601(7894):617-622
pubmed: 34814158
Vaccine. 2021 Oct 29;39(45):6601-6613
pubmed: 34642088
Vaccine. 2020 Jul 31;38(35):5653-5658
pubmed: 32651113
J Immunol. 2009 Nov 15;183(10):6186-97
pubmed: 19864596
Biotechnol Adv. 1991;9(1):51-68
pubmed: 14543739
Vaccine. 2007 Apr 12;25(15):2832-8
pubmed: 17092615
Curr Opin Biotechnol. 2011 Dec;22(6):868-76
pubmed: 21862310
J Virol. 2014 Aug;88(15):8597-614
pubmed: 24850731
Proc Natl Acad Sci U S A. 2020 May 26;117(21):11727-11734
pubmed: 32376634
Expert Rev Vaccines. 2013 Aug;12(8):821-3
pubmed: 23984954
Sci Rep. 2020 Nov 18;10(1):20085
pubmed: 33208827
Vaccine. 2021 Sep 24;39(40):5940-5953
pubmed: 34420786
Clin Exp Immunol. 2020 Nov;202(2):162-192
pubmed: 32935331
Cell Host Microbe. 2020 Apr 8;27(4):671-680.e2
pubmed: 32183941
Biochem Biophys Res Commun. 2004 Nov 12;324(2):773-81
pubmed: 15474494
Clin Transl Immunology. 2021 Apr 05;10(4):e1269
pubmed: 33841880
N Engl J Med. 2020 Dec 10;383(24):2320-2332
pubmed: 32877576
Nature. 2020 Dec;588(7837):327-330
pubmed: 32942285
Immunity. 2020 Dec 15;53(6):1315-1330.e9
pubmed: 33275896
Nat Rev Microbiol. 2021 Mar;19(3):141-154
pubmed: 33024307
Antiviral Res. 2020 Apr;176:104742
pubmed: 32057769
Lancet Respir Med. 2021 Dec;9(12):1396-1406
pubmed: 34655522
Biochemistry (Mosc). 2021 Jul;86(7):800-817
pubmed: 34284707
Cells. 2020 Dec 08;9(12):
pubmed: 33302501
J Biomol Struct Dyn. 2019 Oct;37(16):4345-4360
pubmed: 30457455
Vaccine. 2014 Oct 21;32(46):6170-6176
pubmed: 25240756
Cell Rep. 2021 Mar 30;34(13):108915
pubmed: 33761319
Antiviral Res. 2017 Jan;137:82-92
pubmed: 27840203
Emerg Microbes Infect. 2021 Dec;10(1):1589-1597
pubmed: 34197281
Vaccines (Basel). 2022 Jan 02;10(1):
pubmed: 35062730
Nat Microbiol. 2020 Apr;5(4):536-544
pubmed: 32123347
Virology. 2009 Oct 10;393(1):144-50
pubmed: 19683779
Adv Drug Deliv Rev. 2021 Mar;170:71-82
pubmed: 33421475
EClinicalMedicine. 2022 Jul 22;51:101569
pubmed: 35879941
Lancet Reg Health Am. 2023 Feb;18:100423
pubmed: 36618081
PLoS One. 2014 Nov 18;9(11):e112602
pubmed: 25405618
Virology. 2016 Dec;499:375-382
pubmed: 27750111
EBioMedicine. 2015 Aug 18;2(10):1438-46
pubmed: 26629538
Lancet Infect Dis. 2022 May;22(5):636-648
pubmed: 35090638
Front Immunol. 2021 Apr 22;12:660198
pubmed: 33968063
Immunobiology. 2020 May;225(3):151955
pubmed: 32517882
ACS Infect Dis. 2016 May 13;2(5):361-76
pubmed: 27627203
Expert Rev Vaccines. 2019 May;18(5):505-521
pubmed: 31009255
Hum Vaccin Immunother. 2021 Feb 1;17(2):560-565
pubmed: 32614657
Vaccine. 2017 Feb 22;35(8):1175-1183
pubmed: 28118938
ACS Chem Biol. 2021 Jul 16;16(7):1223-1233
pubmed: 34219448
Front Immunol. 2021 Dec 06;12:766112
pubmed: 34938290
Front Immunol. 2021 Jul 12;12:701501
pubmed: 34322129
J Biomed Sci. 2010 Nov 22;17:88
pubmed: 21092195
Genome Med. 2021 Jun 14;13(1):101
pubmed: 34127050
Nat Rev Mol Cell Biol. 2022 Jan;23(1):3-20
pubmed: 34611326
Vaccine. 2022 May 20;40(23):3182-3192
pubmed: 35465982
Adv Drug Deliv Rev. 2021 May;172:314-338
pubmed: 33482248
Vaccine. 2015 Nov 4;33(44):5920-6
pubmed: 26407920
Lancet Infect Dis. 2021 Oct;21(10):1383-1394
pubmed: 33887208
Infect Drug Resist. 2018 Nov 21;11:2377-2391
pubmed: 30538505
Vaccine. 2021 Nov 26;39(48):7001-7011
pubmed: 34750014
Vaccine. 2022 Jul 30;40(32):4440-4452
pubmed: 35697573
J Clin Invest. 2022 May 16;132(10):
pubmed: 35316221
N Engl J Med. 2022 Feb 10;386(6):531-543
pubmed: 34910859
Cell Rep Med. 2021 Feb 16;2(2):100204
pubmed: 33521695
Antiviral Res. 2017 Aug;144:27-33
pubmed: 28511994
Vaccine. 2019 Jun 27;37(29):3793-3803
pubmed: 31151801
Vaccine. 2022 Feb 23;40(9):1253-1260
pubmed: 35115195
Nat Rev Immunol. 2020 Jun;20(6):363-374
pubmed: 32346093
Front Immunol. 2022 May 26;13:836745
pubmed: 35693788
Exp Cell Res. 2011 May 15;317(9):1261-9
pubmed: 21371474
Eng Life Sci. 2021 May 07;21(6):453-460
pubmed: 34140855
N Engl J Med. 2022 Jun 2;386(22):2097-2111
pubmed: 35507481
Nat Commun. 2021 Jan 14;12(1):372
pubmed: 33446655
Lancet Reg Health West Pac. 2022 May 16;24:100474
pubmed: 35602004
Biophysics (Oxf). 2020;65(4):703-709
pubmed: 33100352
Vaccine. 2006 Apr 12;24(16):3100-8
pubmed: 16494977
J Virol. 2020 Feb 14;94(5):
pubmed: 31826992
Hum Vaccin Immunother. 2020 Dec 1;16(12):2905-2912
pubmed: 33232211