A Simplified Low-Dose 10-Day Quadruple Therapy with a Galenic Formulation of Bismuth Salicylate Is Highly Effective for

Helicobacter pylori infection bismuth salicylate quadruple therapy

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
15 Jan 2023
Historique:
received: 07 12 2022
revised: 11 01 2023
accepted: 13 01 2023
entrez: 21 1 2023
pubmed: 22 1 2023
medline: 22 1 2023
Statut: epublish

Résumé

Earlier studies have shown that a modified low-dose bismuth quadruple therapy given for 10 to 14 days is highly effective for the treatment of We aimed to investigate the efficacy of a simplified low-dose 10-day quadruple therapy containing a galenic formulation of bismuth salicylate for Adult patients positive for In this open-label pilot study, 42 patients were enrolled (mean age 54.1 ± 12.0 years; 64% female). Among the study participants, 35 were naïve to The modified low-dose 10-day quadruple therapy provided high eradication rates of

Sections du résumé

BACKGROUND BACKGROUND
Earlier studies have shown that a modified low-dose bismuth quadruple therapy given for 10 to 14 days is highly effective for the treatment of
AIM OBJECTIVE
We aimed to investigate the efficacy of a simplified low-dose 10-day quadruple therapy containing a galenic formulation of bismuth salicylate for
PATIENTS AND METHODS METHODS
Adult patients positive for
RESULTS RESULTS
In this open-label pilot study, 42 patients were enrolled (mean age 54.1 ± 12.0 years; 64% female). Among the study participants, 35 were naïve to
CONCLUSIONS CONCLUSIONS
The modified low-dose 10-day quadruple therapy provided high eradication rates of

Identifiants

pubmed: 36675610
pii: jcm12020681
doi: 10.3390/jcm12020681
pmc: PMC9861798
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

Gut. 2017 Dec;66(12):2043-2046
pubmed: 28935677
Helicobacter. 2011 Aug;16(4):295-300
pubmed: 21762269
Gut. 2021 Oct;70(10):1815-1822
pubmed: 33837118
Helicobacter. 2018 Sep;23 Suppl 1:e12519
pubmed: 30203585
FEMS Immunol Med Microbiol. 2007 Jul;50(2):249-56
pubmed: 17521391
Cleve Clin J Med. 2017 Apr;84(4):310-318
pubmed: 28388387
Gut. 2017 Jan;66(1):6-30
pubmed: 27707777
Am J Gastroenterol. 2022 Apr 1;117(4):524-528
pubmed: 35081545
Gut. 2022 Mar;71(3):643-650
pubmed: 34750206
Helicobacter. 2005;10 Suppl 1:1-4
pubmed: 16178964
Helicobacter. 1999 Jun;4(2):106-12
pubmed: 10382124
Aliment Pharmacol Ther. 1998 Jul;12(7):635-9
pubmed: 9701526
Clin Gastroenterol Hepatol. 2022 May;20(5):973-983.e1
pubmed: 33775895
Am J Gastroenterol. 2003 Mar;98(3):562-7
pubmed: 12650788
Aliment Pharmacol Ther. 2012 Sep;36(5):414-25
pubmed: 22803691
Helicobacter. 2019 Apr;24(2):e12570
pubmed: 30767339
Med J Aust. 1989 Oct 16;151(8):431-5
pubmed: 2687668
Medicine (Baltimore). 2018 Jan;97(4):e9734
pubmed: 29369216
Am J Gastroenterol. 2002 Apr;97(4):857-60
pubmed: 12003419
Open Forum Infect Dis. 2022 Apr 08;9(6):ofac165
pubmed: 35755772
Med J Aust. 1990 Aug 6;153(3):145-9
pubmed: 1974027
J Clin Gastroenterol. 1996 Jun;22(4):313-6
pubmed: 8771431
Open Forum Infect Dis. 2022 Aug 11;9(8):ofac413
pubmed: 36004310
Annu Rev Med. 2022 Jan 27;73:183-195
pubmed: 35084993
Gastroenterol Clin North Am. 2015 Sep;44(3):537-63
pubmed: 26314667

Auteurs

Maria Pina Dore (MP)

Dipartimento di Medicina, Chirurgia e Farmacia, Clinica Medica, University of Sassari, Viale San Pietro 8, 07100 Sassari, Italy.
Department of Medicine, Baylor College of Medicine, One Baylor Plaza Blvd, Houston, TX 77030, USA.

Francesco Saba (F)

Dipartimento di Medicina, Chirurgia e Farmacia, Clinica Medica, University of Sassari, Viale San Pietro 8, 07100 Sassari, Italy.

Lucia Zanni (L)

Dipartimento di Medicina, Chirurgia e Farmacia, Clinica Medica, University of Sassari, Viale San Pietro 8, 07100 Sassari, Italy.

Anna Rocca (A)

Dipartimento di Medicina, Chirurgia e Farmacia, Clinica Medica, University of Sassari, Viale San Pietro 8, 07100 Sassari, Italy.

Jessica Piroddu (J)

Dipartimento di Medicina, Chirurgia e Farmacia, Clinica Medica, University of Sassari, Viale San Pietro 8, 07100 Sassari, Italy.

Giuseppe Gutierrez (G)

Pharmaceutical Laboratory "Gutierrez-Pisano", 07100 Sassari, Italy.

Giovanni Mario Pes (GM)

Dipartimento di Medicina, Chirurgia e Farmacia, Clinica Medica, University of Sassari, Viale San Pietro 8, 07100 Sassari, Italy.

Classifications MeSH