Monte Carlo-Based Radiobiological Investigation of the Most Optimal Ion Beam Forming SOBP for Particle Therapy.

Monte Carlo heavy ions ion beams particle therapy relative biological effectiveness

Journal

Journal of personalized medicine
ISSN: 2075-4426
Titre abrégé: J Pers Med
Pays: Switzerland
ID NLM: 101602269

Informations de publication

Date de publication:
22 Dec 2022
Historique:
received: 08 11 2022
revised: 13 12 2022
accepted: 21 12 2022
entrez: 21 1 2023
pubmed: 22 1 2023
medline: 22 1 2023
Statut: epublish

Résumé

Proton (p) and carbon (C) ion beams are in clinical use for cancer treatment, although other particles such as He, Be, and B ions have more recently gained attention. Identification of the most optimal ion beam for radiotherapy is a challenging task involving, among others, radiobiological characterization of a beam, which is depth-, energy-, and cell type- dependent. This study uses the FLUKA and MCDS Monte Carlo codes in order to estimate the relative biological effectiveness (RBE) for several ions of potential clinical interest such as p,

Identifiants

pubmed: 36675684
pii: jpm13010023
doi: 10.3390/jpm13010023
pmc: PMC9864401
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Ioannis Kantemiris (I)

Medical Physics Department, Metropolitan Hospital, 18547 Neo Faliro, Greece.

Eleftherios P Pappas (EP)

Medical Physics Laboratory, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.

Georgia Lymperopoulou (G)

1st Department of Radiology, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.

Dimitrios Thanasas (D)

Medical Physics Laboratory, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.

Pantelis Karaiskos (P)

Medical Physics Laboratory, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.

Classifications MeSH