COVID-19 Clusters in Belgian Nursing Homes: Impact of Facility Characteristics and Vaccination on Cluster Occurrence, Duration and Severity.
SARS-CoV-2
clusters
infection prevention
long-term care facilities
vaccination
Journal
Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722
Informations de publication
Date de publication:
13 01 2023
13 01 2023
Historique:
received:
29
11
2022
revised:
06
01
2023
accepted:
09
01
2023
entrez:
21
1
2023
pubmed:
22
1
2023
medline:
25
1
2023
Statut:
epublish
Résumé
COVID-19 severely affected nursing home residents from March 2020 onwards in Belgium. This study aimed to model the impact of vaccination and facility characteristics on cluster occurrence, duration and severity in this setting. Possible clusters were identified between June 2020 and January 2022, based on the Belgian COVID-19 surveillance in nursing homes. Median attack rates (AR) among residents and staff, case hospitalization rates (CHR) and case fatality rates (CFR) were calculated. A negative binomial model was used to identify the association between nursing home characteristics and the number of cases, hospital admissions and deaths and the duration of the cluster. A total of 2239 clusters were detected in more than 80% of nursing homes. Most of these (62%) occurred before the start of COVID-19 vaccination (end of December 2020). After vaccination, the number of clusters, the AR among residents and staff, the CHR and the CFR dropped. Previous cluster(s) and vaccination decreased the number of cases, hospital admissions and deaths among residents. Previous cluster experience and having started vaccination were protective factors. We recommend continued implementation of targeted interventions such as vaccination, large-scale screening and immediate implementation of additional infection prevention and control measures.
Identifiants
pubmed: 36680272
pii: v15010232
doi: 10.3390/v15010232
pmc: PMC9867491
pii:
doi:
Substances chimiques
COVID-19 Vaccines
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Déclaration de conflit d'intérêts
The authors declare no conflicts of interest.
Références
Euro Surveill. 2021 Dec;26(49):
pubmed: 34886946
JAMA Intern Med. 2021 Feb 1;181(2):229-236
pubmed: 33165560
Euro Surveill. 2020 Jun;25(22):
pubmed: 32524949
Epidemics. 2022 Sep;40:100589
pubmed: 35691101
Science. 2021 Apr 9;372(6538):
pubmed: 33658326
Euro Surveill. 2021 Dec;26(48):
pubmed: 34857066
Lancet Healthy Longev. 2021 Mar;2(3):e129-e142
pubmed: 33655236
JMIR Public Health Surveill. 2020 May 26;6(2):e11512
pubmed: 32357126
Lancet Infect Dis. 2021 Apr;21(4):e67
pubmed: 32628906
Arch Public Health. 2022 Jan 29;80(1):45
pubmed: 35093169
Aging Dis. 2022 Apr 1;13(2):402-422
pubmed: 35371608
JAMA Intern Med. 2020 Aug 01;180(8):1101-1105
pubmed: 32437547
J Community Hosp Intern Med Perspect. 2021 Nov 15;11(6):733-739
pubmed: 34804382
Clin Microbiol Infect. 2022 Feb;28(2):279-284
pubmed: 34619398
Epidemiol Infect. 2022 Feb 22;150:e72
pubmed: 35403594
J Am Med Dir Assoc. 2021 Feb;22(2):256-257
pubmed: 33358724
J Am Geriatr Soc. 2020 Aug;68(8):1653-1656
pubmed: 32484912
Vaccine. 2022 Oct 12;40(43):6218-6224
pubmed: 36127210
Clin Infect Dis. 2021 Sep 15;73(6):e1365-e1367
pubmed: 33768222
Cell Rep Med. 2022 Mar 11;3(4):100583
pubmed: 35480627
Lancet Healthy Longev. 2020 Oct;1(1):e21-e31
pubmed: 34173614
Clin Infect Dis. 2021 Jul 30;73(Suppl 2):S163-S169
pubmed: 33119065
JAMA Intern Med. 2022 Jul 1;182(7):701-709
pubmed: 35486394
Viruses. 2022 Jun 22;14(7):
pubmed: 35891341