Multitasking dynamic contrast enhanced magnetic resonance imaging can accurately differentiate chronic pancreatitis from pancreatic ductal adenocarcinoma.
Multitasking DCE
differential diagnosis of chronic pancreatitis and pancreatic ductal adenocarcinoma
dynamic contrast enhanced magnetic resonance imaging
microcirculation properties
quantitative imaging
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2022
2022
Historique:
received:
30
07
2022
accepted:
16
11
2022
entrez:
23
1
2023
pubmed:
24
1
2023
medline:
24
1
2023
Statut:
epublish
Résumé
Accurate differentiation of chronic pancreatitis (CP) and pancreatic ductal adenocarcinoma (PDAC) is an area of unmet clinical need. In this study, a novel Multitasking dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI) technique was used to quantitatively evaluate the microcirculation properties of pancreas in CP and PDAC and differentiate between them. The Multitasking DCE technique was able to acquire one 3D image per second during the passage of MRI contrast agent, allowing the quantitative estimation of microcirculation properties of tissue, including blood flow F Fourteen PDAC patients, 8 CP patients and 20 healthy subjects were prospectively recruited. The combination of F Multitasking DCE MRI is a promising clinical tool that is capable of unbiased quantitative differentiation between CP from PDAC.
Sections du résumé
Background and aims
UNASSIGNED
Accurate differentiation of chronic pancreatitis (CP) and pancreatic ductal adenocarcinoma (PDAC) is an area of unmet clinical need. In this study, a novel Multitasking dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI) technique was used to quantitatively evaluate the microcirculation properties of pancreas in CP and PDAC and differentiate between them.
Methods
UNASSIGNED
The Multitasking DCE technique was able to acquire one 3D image per second during the passage of MRI contrast agent, allowing the quantitative estimation of microcirculation properties of tissue, including blood flow F
Results
UNASSIGNED
Fourteen PDAC patients, 8 CP patients and 20 healthy subjects were prospectively recruited. The combination of F
Conclusion
UNASSIGNED
Multitasking DCE MRI is a promising clinical tool that is capable of unbiased quantitative differentiation between CP from PDAC.
Identifiants
pubmed: 36686811
doi: 10.3389/fonc.2022.1007134
pmc: PMC9853434
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1007134Subventions
Organisme : NIBIB NIH HHS
ID : R01 EB028146
Pays : United States
Organisme : NIBIB NIH HHS
ID : R01 EB032801
Pays : United States
Informations de copyright
Copyright © 2023 Wang, Gaddam, Xie, Christodoulou, Wu, Ma, Fan, Wang, Lo, Hendifar, Pandol and Li.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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