Synthesis and immunopharmacological evaluation of novel TLR7 agonistic triazole tethered imidazoquinolines.
Journal
RSC advances
ISSN: 2046-2069
Titre abrégé: RSC Adv
Pays: England
ID NLM: 101581657
Informations de publication
Date de publication:
03 Jan 2023
03 Jan 2023
Historique:
received:
11
10
2022
accepted:
10
11
2022
entrez:
23
1
2023
pubmed:
24
1
2023
medline:
24
1
2023
Statut:
epublish
Résumé
Toll-like receptors-7 and -8 are expressed abundantly on antigen-presenting cells, and their agonists make potential adjuvant candidates for the development of new efficacious vaccines. In view of the importance of new efficacious imidazoquinoline based adjuvants, herein we have synthesized a focused library of a new class of imidazoquinolines retaining the
Identifiants
pubmed: 36686935
doi: 10.1039/d2ra06395f
pii: d2ra06395f
pmc: PMC9811562
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1066-1077Informations de copyright
This journal is © The Royal Society of Chemistry.
Déclaration de conflit d'intérêts
There are no conflicts to declare.
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