E, K, B5, B6, and B9 vitamins and their specific immunological effects evaluated by flow cytometry.

anticancer diseases flow cytometry immunology vitamins

Journal

Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047

Informations de publication

Date de publication:
2022
Historique:
received: 04 11 2022
accepted: 12 12 2022
entrez: 23 1 2023
pubmed: 24 1 2023
medline: 24 1 2023
Statut: epublish

Résumé

It has been proven that vitamins play an essential role in preventing certain diseases since ancient times. It is thus fruitless to approach the roles of vitamins without making reference to the techniques used in evaluating the effects of these micronutrients. Therefore, the aim of this paper was to summarize the immunological effects of E, K, B5, B6, and B9 vitamins evaluated by flow cytometry. Some of these significant effects were presented and discussed: (a) The role of vitamins E in the prevention and treatment of different types of cancer. (b) The properties of K vitamins in the development and maintenance of pheochromocytoma Cell Line 12 (PC12) cells in Parkinson's disease; (c) The improvement effect of vitamin B5 on the loss of bone mass in low estrogen conditions; (d) The anticancer role of vitamins B6. (e) The role of Vitamin B9 in the regulation of Treg cells. As such, the flow cytometry technique used to assess these properties is essential to evaluate the immunomodulatory effects of certain vitamins. The technique undergoes constant improvement which makes it possible to determine several parameters with a role in the modulation of the immune function and at the same time increase the accuracy of the methods that highlight them.

Identifiants

pubmed: 36687400
doi: 10.3389/fmed.2022.1089476
pmc: PMC9849766
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

1089476

Informations de copyright

Copyright © 2023 Munteanu, Berindean, Mihai, Pop, Popa, Muntean, Petrescu and Ona.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Camelia Munteanu (C)

Department of Plant Culture, Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania.

Ioana Berindean (I)

Department of Plant Culture, Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania.

Mihaela Mihai (M)

Department of Transversal Competencies, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania.

Bianca Pop (B)

Department of Plant Culture, Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania.

Mihai Popa (M)

Department of Plant Culture, Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania.

Leon Muntean (L)

Department of Plant Culture, Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania.

Olivia Petrescu (O)

Department of Applied Modern Languages, Faculty of Letters, Babeş-Bolyai University, Cluj-Napoca, Romania.

Andreea Ona (A)

Department of Plant Culture, Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania.

Classifications MeSH